DE TRPA1

Pre-processing of the data

ls_preprocessed <- preprocess_rna(path_rnaseq = 'rnaseq.RData', correct_batch = T, correct_gender = T)

Exploring data

Batch effect correction

print(ls_preprocessed$pbatch_bf)

print(ls_preprocessed$pgender_bf)

print(ls_preprocessed$pbatch_af)

print(ls_preprocessed$pgender_af)

DE analysis

gn <- as.character(ls_preprocessed$rna_all$Feature[which(ls_preprocessed$rna_all$Feature_gene_name =='TRPA1')])
DE_res <- DE_analysis(ls_preprocessed, 
           GeneBased=TRUE, 
           pDataBased=FALSE,
           NewCondition=FALSE,
           cond_nm=gn,
           reference = 'low', 
           correct_gender=TRUE,
           extremes_only=TRUE)

## Unlist done

## Labeling done

## Filtering done

## factor levels were dropped which had no samples

## Design done

## factor levels were dropped which had no samples

## Warning: Setting row names on a tibble is deprecated.

## vsd symbols done

## using pre-existing size factors

## estimating dispersions

## gene-wise dispersion estimates

## mean-dispersion relationship

## final dispersion estimates

## fitting model and testing

## -- replacing outliers and refitting for 1610 genes
## -- DESeq argument 'minReplicatesForReplace' = 7 
## -- original counts are preserved in counts(dds)

## estimating dispersions

## fitting model and testing

## DESeq done

## using 'normal' for LFC shrinkage, the Normal prior from Love et al (2014).
## 
## Note that type='apeglm' and type='ashr' have shown to have less bias than type='normal'.
## See ?lfcShrink for more details on shrinkage type, and the DESeq2 vignette.
## Reference: https://doi.org/10.1093/bioinformatics/bty895

## res symbols done

## list done

DE results

heatmap_200(DE_res$res_df, DE_res$vsd_mat_sym, DE_res$meta_data, DE_res$pData_rnaseq)

x <- DE_res$res_df %>%
  arrange(desc(abs(log2FoldChange)))
rownames(x) <- make.names(x$symbol, unique = T)
k <- gn
x <- x[-which(x$gene %in%k),]
#head(x, 10)
vp <- volcano_plot(x, gene=NULL, p_title='TRPA1', pCutoff=0.001, FCcutoff=1.5)

List of genes differentially expressed (-1.5 > fold change > 1.5, pval<0.001)

vp_tb <- vp$data[which(vp$data$Sig == 'FC_P'),]
rownames(vp_tb) <- c(1:nrow(vp_tb))
kable(vp_tb)

baseMean	log2FoldChange	lfcSE	stat	pvalue	padj	gene	symbol	Sig	lab	xvals	yvals
4.028480e+01	3.626802	0.4659044	5.487729	0.0000000	0.0000078	ENSG00000159217.5	IGF2BP1	FC_P	IGF2BP1	3.626802	0.0000000
1.424362e+00	3.355930	0.4606525	3.638648	0.0002741	0.0046421	ENSG00000228277.1	AC112518.3	FC_P	AC112518.3	3.355930	0.0002741
1.573867e+01	3.283034	0.4063926	5.259932	0.0000001	0.0000198	ENSG00000180861.5	C12orf36	FC_P	C12orf36	3.283034	0.0000001
1.149603e+01	3.138224	0.4892570	6.732248	0.0000000	0.0000000	ENSG00000106031.6	HOXA13	FC_P	HOXA13	3.138224	0.0000000
9.013161e+01	2.968389	0.4211908	4.135687	0.0000354	0.0011107	ENSG00000094755.12	GABRP	FC_P	GABRP	2.968389	0.0000354
3.826809e+00	2.947610	0.4044187	3.577355	0.0003471	0.0054243	ENSG00000267654.1	RP11-973H7.4	FC_P	RP11.973H7.4	2.947610	0.0003471
5.133828e+02	-2.847745	0.4942222	-5.969964	0.0000000	0.0000010	ENSG00000125851.5	PCSK2	FC_P	PCSK2	-2.847745	0.0000000
6.496843e+00	2.766322	0.4965835	3.992619	0.0000653	0.0017028	ENSG00000102837.6	OLFM4	FC_P	OLFM4	2.766322	0.0000653
3.778181e+02	-2.721969	0.4038448	-6.742470	0.0000000	0.0000000	ENSG00000134020.6	PEBP4	FC_P	PEBP4	-2.721969	0.0000000
1.129898e+01	2.671664	0.3956415	6.587470	0.0000000	0.0000001	ENSG00000268941.1	MGC4294	FC_P	MGC4294	2.671664	0.0000000
2.579193e+01	2.651873	0.4733306	5.485955	0.0000000	0.0000078	ENSG00000227964.1	RP5-1112F19.2	FC_P	RP5.1112F19.2	2.651873	0.0000000
9.768352e+00	2.626679	0.4712190	5.508101	0.0000000	0.0000072	ENSG00000188624.2	IGFL3	FC_P	IGFL3	2.626679	0.0000000
8.810358e+00	2.607049	0.4396776	5.829855	0.0000000	0.0000020	ENSG00000273388.1	RP11-401O9.4	FC_P	RP11.401O9.4	2.607049	0.0000000
7.545176e+00	2.580077	0.4690340	5.589482	0.0000000	0.0000052	ENSG00000263655.1	RP11-25L3.3	FC_P	RP11.25L3.3	2.580077	0.0000000
5.905923e+01	2.573387	0.3597944	7.121725	0.0000000	0.0000000	ENSG00000221502.1	MIR1245A	FC_P	MIR1245A	2.573387	0.0000000
6.789361e+00	2.571106	0.4457182	3.956631	0.0000760	0.0019080	ENSG00000179083.5	FAM133A	FC_P	FAM133A	2.571106	0.0000760
3.120361e+01	2.548871	0.4433360	3.619675	0.0002950	0.0048839	ENSG00000006611.11	USH1C	FC_P	USH1C	2.548871	0.0002950
1.245316e+01	2.526598	0.4976622	5.133755	0.0000003	0.0000327	ENSG00000270470.1	RP11-601H16.1	FC_P	RP11.601H16.1	2.526598	0.0000003
2.657587e+00	-2.519457	0.4675004	-3.858432	0.0001141	0.0025211	ENSG00000241032.2	RN7SL709P	FC_P	RN7SL709P	-2.519457	0.0001141
2.548350e+01	2.497027	0.4089348	6.090872	0.0000000	0.0000007	ENSG00000133020.4	MYH8	FC_P	MYH8	2.497027	0.0000000
3.875403e+03	-2.494320	0.3624571	-6.861474	0.0000000	0.0000000	ENSG00000099994.10	SUSD2	FC_P	SUSD2	-2.494320	0.0000000
1.221030e+03	-2.488812	0.4661348	-4.056469	0.0000498	0.0014043	ENSG00000160862.8	AZGP1	FC_P	AZGP1	-2.488812	0.0000498
4.783482e+00	2.478545	0.4897573	5.042099	0.0000005	0.0000477	ENSG00000272609.1	RP11-461M2.2	FC_P	RP11.461M2.2	2.478545	0.0000005
7.998123e+00	2.456517	0.4532655	5.402242	0.0000001	0.0000115	ENSG00000258162.1	RP11-315E17.1	FC_P	RP11.315E17.1	2.456517	0.0000001
4.217041e+03	-2.432684	0.3288215	-7.381278	0.0000000	0.0000000	ENSG00000259803.2	SLC22A31	FC_P	SLC22A31	-2.432684	0.0000000
4.387781e+00	2.431140	0.4857152	5.164646	0.0000002	0.0000291	ENSG00000233358.2	RP1-209A6.1	FC_P	RP1.209A6.1	2.431140	0.0000002
5.698541e+01	2.423968	0.3550291	6.939605	0.0000000	0.0000000	ENSG00000228073.1	AC133106.2	FC_P	AC133106.2	2.423968	0.0000000
1.111433e+01	2.400156	0.4015238	5.919881	0.0000000	0.0000013	ENSG00000252365.1	SNORD22	FC_P	SNORD22	2.400156	0.0000000
8.098198e+00	2.396787	0.4007783	5.852712	0.0000000	0.0000018	ENSG00000255465.3	RP11-264E20.1	FC_P	RP11.264E20.1	2.396787	0.0000000
1.186326e+01	-2.392555	0.4858690	-5.069842	0.0000004	0.0000423	ENSG00000256288.1	RP11-277P12.10	FC_P	RP11.277P12.10	-2.392555	0.0000004
5.488338e+03	-2.384848	0.4762425	-4.912572	0.0000009	0.0000773	ENSG00000164265.4	SCGB3A2	FC_P	SCGB3A2	-2.384848	0.0000009
1.225651e+03	-2.376766	0.3282488	-7.239266	0.0000000	0.0000000	ENSG00000110195.7	FOLR1	FC_P	FOLR1	-2.376766	0.0000000
1.933385e+01	2.366707	0.4019254	5.903471	0.0000000	0.0000014	ENSG00000183671.8	GPR1	FC_P	GPR1	2.366707	0.0000000
2.490769e+01	2.357796	0.3071271	3.946195	0.0000794	0.0019629	ENSG00000114638.3	UPK1B	FC_P	UPK1B	2.357796	0.0000794
9.942546e+00	2.350478	0.4977219	4.781046	0.0000017	0.0001256	ENSG00000234257.1	SOD2P1	FC_P	SOD2P1	2.350478	0.0000017
2.099978e+02	2.349124	0.2828459	8.265325	0.0000000	0.0000000	ENSG00000226674.4	TEX41	FC_P	TEX41	2.349124	0.0000000
9.958836e+00	2.342077	0.4494404	5.224976	0.0000002	0.0000226	ENSG00000268053.1	CTC-344H19.6	FC_P	CTC.344H19.6	2.342077	0.0000002
4.610169e+00	2.341139	0.4566466	5.138629	0.0000003	0.0000320	ENSG00000270160.1	RP11-264E20.2	FC_P	RP11.264E20.2	2.341139	0.0000003
1.125173e+01	2.340613	0.4711577	4.764147	0.0000019	0.0001340	ENSG00000248837.1	RP11-412P11.1	FC_P	RP11.412P11.1	2.340613	0.0000019
1.887680e+01	2.332277	0.4178825	5.646965	0.0000000	0.0000040	ENSG00000180785.8	OR51E1	FC_P	OR51E1	2.332277	0.0000000
9.435161e+01	2.322566	0.5030797	3.520361	0.0004310	0.0063324	ENSG00000134757.4	DSG3	FC_P	DSG3	2.322566	0.0004310
2.506854e+02	2.316234	0.4337856	5.543327	0.0000000	0.0000062	ENSG00000106236.3	NPTX2	FC_P	NPTX2	2.316234	0.0000000
5.907840e+01	2.311068	0.4355514	5.237887	0.0000002	0.0000214	ENSG00000125285.4	SOX21	FC_P	SOX21	2.311068	0.0000002
9.220039e+03	-2.309385	0.4917065	-5.671039	0.0000000	0.0000037	ENSG00000096088.12	PGC	FC_P	PGC	-2.309385	0.0000000
3.569767e+00	2.294205	0.4732699	4.669650	0.0000030	0.0001881	ENSG00000253257.1	MTND4P7	FC_P	MTND4P7	2.294205	0.0000030
4.437219e+02	-2.289458	0.4814100	-4.791446	0.0000017	0.0001218	ENSG00000078725.8	BRINP1	FC_P	BRINP1	-2.289458	0.0000017
5.084426e+01	2.283251	0.3616751	6.449639	0.0000000	0.0000001	ENSG00000138435.10	CHRNA1	FC_P	CHRNA1	2.283251	0.0000000
4.131516e+01	2.282490	0.4198733	5.278943	0.0000001	0.0000186	ENSG00000227640.2	SOX21-AS1	FC_P	SOX21.AS1	2.282490	0.0000001
3.626056e+01	2.279822	0.3872608	6.033349	0.0000000	0.0000008	ENSG00000181211.1	HECW1-IT1	FC_P	HECW1.IT1	2.279822	0.0000000
2.470736e+01	2.267670	0.3970820	5.678684	0.0000000	0.0000036	ENSG00000172156.3	CCL11	FC_P	CCL11	2.267670	0.0000000
2.229380e+01	-2.265513	0.4935554	-5.085880	0.0000004	0.0000394	ENSG00000223784.1	RP11-554I8.2	FC_P	RP11.554I8.2	-2.265513	0.0000004
6.001026e+01	2.252804	0.3973591	5.790225	0.0000000	0.0000023	ENSG00000006788.8	MYH13	FC_P	MYH13	2.252804	0.0000000
3.135205e+01	2.247554	0.3656291	6.100956	0.0000000	0.0000006	ENSG00000261039.1	RP11-417E7.2	FC_P	RP11.417E7.2	2.247554	0.0000000
8.306776e+01	-2.247382	0.4711635	-4.832835	0.0000013	0.0001041	ENSG00000183607.5	GKN2	FC_P	GKN2	-2.247382	0.0000013
1.024752e+04	2.239805	0.3454676	6.448853	0.0000000	0.0000001	ENSG00000111799.16	COL12A1	FC_P	COL12A1	2.239805	0.0000000
1.480568e+01	2.228556	0.4581424	4.799246	0.0000016	0.0001179	ENSG00000205212.3	CCDC144NL	FC_P	CCDC144NL	2.228556	0.0000016
2.063997e+01	2.222814	0.3802513	5.778862	0.0000000	0.0000024	ENSG00000223485.1	RP11-417E7.1	FC_P	RP11.417E7.1	2.222814	0.0000000
2.106505e+03	-2.220860	0.3636988	-6.085214	0.0000000	0.0000007	ENSG00000153446.11	C16orf89	FC_P	C16orf89	-2.220860	0.0000000
7.686817e+00	2.217684	0.4311008	4.783421	0.0000017	0.0001251	ENSG00000224173.1	AC007422.1	FC_P	AC007422.1	2.217684	0.0000017
1.677209e+02	2.216544	0.3592180	6.179232	0.0000000	0.0000005	ENSG00000196460.8	RFX8	FC_P	RFX8	2.216544	0.0000000
1.950384e+00	2.207120	0.4855367	4.504662	0.0000066	0.0003276	ENSG00000225811.1	RP11-547I7.1	FC_P	RP11.547I7.1	2.207120	0.0000066
7.987036e+01	-2.197739	0.4633436	-4.647219	0.0000034	0.0002040	ENSG00000254872.2	RP13-870H17.3	FC_P	RP13.870H17.3	-2.197739	0.0000034
1.033591e+01	2.195211	0.4678897	5.126861	0.0000003	0.0000336	ENSG00000136535.10	TBR1	FC_P	TBR1	2.195211	0.0000003
1.521901e+01	-2.194363	0.4697889	-4.725241	0.0000023	0.0001526	ENSG00000160339.11	FCN2	FC_P	FCN2	-2.194363	0.0000023
2.225191e+01	2.189923	0.4217611	5.367369	0.0000001	0.0000132	ENSG00000249378.1	LINC01060	FC_P	LINC01060	2.189923	0.0000001
4.054495e+03	-2.189554	0.4412982	-4.951077	0.0000007	0.0000667	ENSG00000187134.8	AKR1C1	FC_P	AKR1C1	-2.189554	0.0000007
1.316624e+01	2.188548	0.3749933	5.865388	0.0000000	0.0000017	ENSG00000147145.8	LPAR4	FC_P	LPAR4	2.188548	0.0000000
3.394053e+02	2.181681	0.3723500	5.807798	0.0000000	0.0000022	ENSG00000152377.8	SPOCK1	FC_P	SPOCK1	2.181681	0.0000000
3.458778e+01	-2.180275	0.4611739	-4.565480	0.0000050	0.0002700	ENSG00000236242.1	MYO16-AS1	FC_P	MYO16.AS1	-2.180275	0.0000050
2.094386e+01	2.178625	0.4880944	5.308163	0.0000001	0.0000168	ENSG00000154162.9	CDH12	FC_P	CDH12	2.178625	0.0000001
2.506915e+00	2.175533	0.4545993	4.602971	0.0000042	0.0002387	ENSG00000267057.1	RP11-456O19.2	FC_P	RP11.456O19.2	2.175533	0.0000042
1.061834e+01	2.162642	0.4073773	5.292260	0.0000001	0.0000176	ENSG00000236857.3	RP11-503K16.2	FC_P	RP11.503K16.2	2.162642	0.0000001
7.353497e+00	2.159691	0.3608171	5.912765	0.0000000	0.0000013	ENSG00000251756.1	RNA5SP385	FC_P	RNA5SP385	2.159691	0.0000000
2.814973e+03	-2.155948	0.3420383	-6.357094	0.0000000	0.0000002	ENSG00000162551.9	ALPL	FC_P	ALPL	-2.155948	0.0000000
4.357097e+02	-2.155729	0.4336485	-4.998878	0.0000006	0.0000562	ENSG00000130234.6	ACE2	FC_P	ACE2	-2.155729	0.0000006
4.123281e+01	2.153215	0.4136499	5.181757	0.0000002	0.0000268	ENSG00000187546.9	AGMO	FC_P	AGMO	2.153215	0.0000002
1.692727e+01	2.146463	0.4369202	4.849280	0.0000012	0.0000991	ENSG00000140557.7	ST8SIA2	FC_P	ST8SIA2	2.146463	0.0000012
3.381668e+00	2.138464	0.4661688	4.400423	0.0000108	0.0004696	ENSG00000270058.1	RP11-514D23.3	FC_P	RP11.514D23.3	2.138464	0.0000108
2.149554e+02	-2.138047	0.3505118	-6.165692	0.0000000	0.0000005	ENSG00000166823.5	MESP1	FC_P	MESP1	-2.138047	0.0000000
1.951839e+02	-2.133977	0.4592704	-4.563709	0.0000050	0.0002711	ENSG00000134216.14	CHIA	FC_P	CHIA	-2.133977	0.0000050
1.678809e+01	2.130520	0.3917952	5.399256	0.0000001	0.0000116	ENSG00000229720.1	RP3-495K2.2	FC_P	RP3.495K2.2	2.130520	0.0000001
1.760878e+02	2.123271	0.3204636	6.633649	0.0000000	0.0000001	ENSG00000271811.1	RP1-79C4.4	FC_P	RP1.79C4.4	2.123271	0.0000000
1.290192e+02	2.122422	0.4096057	5.248492	0.0000002	0.0000205	ENSG00000155886.7	SLC24A2	FC_P	SLC24A2	2.122422	0.0000002
3.945995e+04	-2.120268	0.5010524	-4.298868	0.0000172	0.0006547	ENSG00000161055.3	SCGB3A1	FC_P	SCGB3A1	-2.120268	0.0000172
2.079858e+03	2.119308	0.4396303	4.790849	0.0000017	0.0001220	ENSG00000166923.6	GREM1	FC_P	GREM1	2.119308	0.0000017
2.453865e+02	2.116091	0.2163756	9.765045	0.0000000	0.0000000	ENSG00000235531.5	RP11-383H13.1	FC_P	RP11.383H13.1	2.116091	0.0000000
1.787521e+02	2.112770	0.3316345	6.295440	0.0000000	0.0000003	ENSG00000261425.1	RP11-709B3.2	FC_P	RP11.709B3.2	2.112770	0.0000000
1.298746e+02	-2.112450	0.4236110	-4.955374	0.0000007	0.0000660	ENSG00000149435.8	GGTLC1	FC_P	GGTLC1	-2.112450	0.0000007
3.168742e+02	2.109450	0.4726325	4.433305	0.0000093	0.0004194	ENSG00000270597.1	IGHV3-48	FC_P	IGHV3.48	2.109450	0.0000093
5.749615e+01	2.101717	0.3860959	5.529237	0.0000000	0.0000066	ENSG00000204866.4	IGFL2	FC_P	IGFL2	2.101717	0.0000000
2.120834e+00	2.097159	0.4887251	4.276831	0.0000190	0.0007051	ENSG00000238202.1	AC002465.2	FC_P	AC002465.2	2.097159	0.0000190
1.734527e+01	2.096525	0.3371800	6.211210	0.0000000	0.0000004	ENSG00000241942.2	RPS20P20	FC_P	RPS20P20	2.096525	0.0000000
4.743236e+01	2.094334	0.3469510	6.010647	0.0000000	0.0000009	ENSG00000255311.1	RP11-160H12.2	FC_P	RP11.160H12.2	2.094334	0.0000000
3.047785e+00	2.093679	0.4848868	4.281024	0.0000186	0.0006960	ENSG00000234519.1	RP3-495K2.1	FC_P	RP3.495K2.1	2.093679	0.0000186
8.409952e+00	2.092551	0.4957340	4.299200	0.0000171	0.0006547	ENSG00000268580.1	RP11-514A9.1	FC_P	RP11.514A9.1	2.092551	0.0000171
3.194752e+00	2.090153	0.4206772	4.804394	0.0000016	0.0001158	ENSG00000264838.1	AP003305.1	FC_P	AP003305.1	2.090153	0.0000016
2.133358e+00	2.077162	0.5015148	4.175187	0.0000298	0.0009775	ENSG00000224932.1	AC107399.2	FC_P	AC107399.2	2.077162	0.0000298
1.544109e+02	2.073299	0.3999376	5.000625	0.0000006	0.0000560	ENSG00000139292.8	LGR5	FC_P	LGR5	2.073299	0.0000006
1.882769e+02	-2.072491	0.4451086	-4.557522	0.0000052	0.0002765	ENSG00000116183.6	PAPPA2	FC_P	PAPPA2	-2.072491	0.0000052
3.121130e+01	2.071562	0.3868603	5.326675	0.0000001	0.0000155	ENSG00000235784.2	HNRNPA1P29	FC_P	HNRNPA1P29	2.071562	0.0000001
1.631935e+04	-2.061623	0.3418241	-6.022795	0.0000000	0.0000008	ENSG00000131400.3	NAPSA	FC_P	NAPSA	-2.061623	0.0000000
1.106924e+01	2.058248	0.3976349	5.138573	0.0000003	0.0000320	ENSG00000260832.1	CTD-3253I12.1	FC_P	CTD.3253I12.1	2.058248	0.0000003
1.133117e+03	-2.057015	0.3984525	-5.112513	0.0000003	0.0000357	ENSG00000144331.14	ZNF385B	FC_P	ZNF385B	-2.057015	0.0000003
2.012311e+01	2.055935	0.3252615	6.321256	0.0000000	0.0000002	ENSG00000257467.1	RP11-121G22.3	FC_P	RP11.121G22.3	2.055935	0.0000000
1.565484e+02	2.055794	0.4392295	5.153993	0.0000003	0.0000302	ENSG00000248810.1	RP11-362F19.1	FC_P	RP11.362F19.1	2.055794	0.0000003
6.330544e+00	-2.046799	0.4761282	-4.188854	0.0000280	0.0009362	ENSG00000199687.1	RNU1-38P	FC_P	RNU1.38P	-2.046799	0.0000280
7.981835e+02	2.038297	0.4031244	5.037420	0.0000005	0.0000484	ENSG00000172061.7	LRRC15	FC_P	LRRC15	2.038297	0.0000005
3.140975e+01	2.037127	0.4477999	5.160263	0.0000002	0.0000295	ENSG00000176177.9	ENTHD1	FC_P	ENTHD1	2.037127	0.0000002
2.513557e+00	2.036646	0.4809516	4.027302	0.0000564	0.0015340	ENSG00000252960.1	RN7SKP258	FC_P	RN7SKP258	2.036646	0.0000564
7.631467e+00	2.035883	0.3977353	5.080448	0.0000004	0.0000402	ENSG00000248730.1	EGFLAM-AS4	FC_P	EGFLAM.AS4	2.035883	0.0000004
4.235775e+02	-2.033415	0.4684187	-4.707338	0.0000025	0.0001624	ENSG00000162006.5	MSLNL	FC_P	MSLNL	-2.033415	0.0000025
6.203193e+00	2.030889	0.4518481	4.620106	0.0000038	0.0002232	ENSG00000227972.1	PRKRIRP3	FC_P	PRKRIRP3	2.030889	0.0000038
1.022620e+02	2.026062	0.3760071	5.367675	0.0000001	0.0000132	ENSG00000140873.11	ADAMTS18	FC_P	ADAMTS18	2.026062	0.0000001
6.985192e+02	2.024818	0.3452157	5.923695	0.0000000	0.0000013	ENSG00000140285.5	FGF7	FC_P	FGF7	2.024818	0.0000000
1.454041e+02	2.021982	0.3815566	5.706063	0.0000000	0.0000033	ENSG00000198796.6	ALPK2	FC_P	ALPK2	2.021982	0.0000000
1.938031e+01	2.021395	0.4450648	4.286507	0.0000182	0.0006825	ENSG00000172020.8	GAP43	FC_P	GAP43	2.021395	0.0000182
5.578032e+01	2.018014	0.3153955	6.538233	0.0000000	0.0000001	ENSG00000254141.1	RP11-642D21.1	FC_P	RP11.642D21.1	2.018014	0.0000000
2.006632e+01	-2.016221	0.4658165	-4.373705	0.0000122	0.0005100	ENSG00000238129.1	RP3-410C9.2	FC_P	RP3.410C9.2	-2.016221	0.0000122
4.110036e+01	2.014728	0.4126117	4.846195	0.0000013	0.0000996	ENSG00000264424.1	MYH4	FC_P	MYH4	2.014728	0.0000013
4.796366e+02	2.013829	0.4464127	4.634523	0.0000036	0.0002132	ENSG00000197301.3	RP11-366L20.2	FC_P	RP11.366L20.2	2.013829	0.0000036
1.160020e+01	2.013720	0.3852257	5.123695	0.0000003	0.0000339	ENSG00000257835.1	RP1-97G4.1	FC_P	RP1.97G4.1	2.013720	0.0000003
4.919609e+01	2.009160	0.3497751	5.722716	0.0000000	0.0000031	ENSG00000250979.1	RP11-656G20.1	FC_P	RP11.656G20.1	2.009160	0.0000000
5.642299e+00	2.007967	0.4351011	4.496229	0.0000069	0.0003373	ENSG00000249002.2	RP11-358D17.1	FC_P	RP11.358D17.1	2.007967	0.0000069
3.561952e+02	-2.006176	0.3904788	-5.273065	0.0000001	0.0000189	ENSG00000137709.5	POU2F3	FC_P	POU2F3	-2.006176	0.0000001
1.455849e+01	2.004521	0.3538434	5.553408	0.0000000	0.0000060	ENSG00000267976.1	AP000695.1	FC_P	AP000695.1	2.004521	0.0000000
4.460057e+00	2.003158	0.4253608	4.628817	0.0000037	0.0002174	ENSG00000219149.4	RP11-214N16.2	FC_P	RP11.214N16.2	2.003158	0.0000037
1.578828e+02	-2.001891	0.4731295	-4.262294	0.0000202	0.0007374	ENSG00000214856.7	KRT16P1	FC_P	KRT16P1	-2.001891	0.0000202
3.189104e+01	-1.999823	0.4563880	-4.398698	0.0000109	0.0004718	ENSG00000256969.1	RP11-320N7.2	FC_P	RP11.320N7.2	-1.999823	0.0000109
1.047687e+01	1.998082	0.3967055	4.939518	0.0000008	0.0000693	ENSG00000206129.3	CTD-2008L17.2	FC_P	CTD.2008L17.2	1.998082	0.0000008
1.565883e+01	1.997523	0.4282409	4.687335	0.0000028	0.0001752	ENSG00000269729.1	AC006262.4	FC_P	AC006262.4	1.997523	0.0000028
2.129264e+00	-1.994031	0.4919320	-4.045253	0.0000523	0.0014547	ENSG00000237736.1	U82670.4	FC_P	U82670.4	-1.994031	0.0000523
2.699970e+01	1.992843	0.3715440	5.392477	0.0000001	0.0000119	ENSG00000125414.14	MYH2	FC_P	MYH2	1.992843	0.0000001
1.728521e+01	1.990319	0.4469574	4.372215	0.0000123	0.0005124	ENSG00000259518.1	RP11-597K23.2	FC_P	RP11.597K23.2	1.990319	0.0000123
1.248054e+01	1.990218	0.4002871	5.093220	0.0000004	0.0000386	ENSG00000239119.1	RNU7-119P	FC_P	RNU7.119P	1.990218	0.0000004
2.235047e+02	-1.985942	0.3210853	-6.124276	0.0000000	0.0000006	ENSG00000186493.7	C5orf38	FC_P	C5orf38	-1.985942	0.0000000
1.052814e+01	1.984119	0.4531889	4.428345	0.0000095	0.0004276	ENSG00000232821.1	AC003986.6	FC_P	AC003986.6	1.984119	0.0000095
8.144177e+00	1.983548	0.4105649	4.789345	0.0000017	0.0001222	ENSG00000205221.8	VIT	FC_P	VIT	1.983548	0.0000017
1.996954e+01	1.982978	0.3950730	4.954547	0.0000007	0.0000662	ENSG00000135312.4	HTR1B	FC_P	HTR1B	1.982978	0.0000007
5.086739e+03	-1.981489	0.4587420	-4.560211	0.0000051	0.0002737	ENSG00000102854.10	MSLN	FC_P	MSLN	-1.981489	0.0000051
3.596240e+00	1.981137	0.4940496	3.688318	0.0002257	0.0040381	ENSG00000235690.2	CUBNP3	FC_P	CUBNP3	1.981137	0.0002257
1.118685e+01	1.980457	0.5028325	4.403912	0.0000106	0.0004636	ENSG00000251129.1	RP11-734I18.1	FC_P	RP11.734I18.1	1.980457	0.0000106
7.844710e+00	1.979272	0.4517187	4.342473	0.0000141	0.0005666	ENSG00000257228.1	RP11-413B19.2	FC_P	RP11.413B19.2	1.979272	0.0000141
6.066636e+02	1.973520	0.4459381	4.728077	0.0000023	0.0001516	ENSG00000007908.11	SELE	FC_P	SELE	1.973520	0.0000023
1.396606e+01	-1.972928	0.4317993	-4.529418	0.0000059	0.0003033	ENSG00000235836.1	AC124944.4	FC_P	AC124944.4	-1.972928	0.0000059
4.907888e+00	1.972376	0.4093144	4.742580	0.0000021	0.0001449	ENSG00000261103.1	RP11-298D21.3	FC_P	RP11.298D21.3	1.972376	0.0000021
2.698864e+03	1.972181	0.4718008	4.305312	0.0000167	0.0006385	ENSG00000060718.14	COL11A1	FC_P	COL11A1	1.972181	0.0000167
4.447818e+02	-1.967668	0.4916436	-3.887694	0.0001012	0.0023231	ENSG00000223414.2	LINC00473	FC_P	LINC00473	-1.967668	0.0001012
6.218876e+00	-1.967194	0.3986477	-4.823443	0.0000014	0.0001085	ENSG00000236887.1	RP11-389O22.5	FC_P	RP11.389O22.5	-1.967194	0.0000014
2.971088e+00	1.966319	0.4863656	3.805729	0.0001414	0.0029234	ENSG00000231324.1	AP000696.2	FC_P	AP000696.2	1.966319	0.0001414
1.768157e+01	1.965745	0.4315610	4.845775	0.0000013	0.0000996	ENSG00000264660.1	RP11-381P6.1	FC_P	RP11.381P6.1	1.965745	0.0000013
6.558839e+01	-1.961485	0.4514084	-4.362646	0.0000128	0.0005275	ENSG00000233067.2	RP11-40F8.2	FC_P	RP11.40F8.2	-1.961485	0.0000128
3.001469e+00	1.959067	0.4692267	4.205708	0.0000260	0.0008824	ENSG00000253746.1	RP11-527N22.2	FC_P	RP11.527N22.2	1.959067	0.0000260
3.493446e+00	1.957117	0.4328621	4.403756	0.0000106	0.0004636	ENSG00000248698.1	LINC01085	FC_P	LINC01085	1.957117	0.0000106
5.409571e+03	-1.956457	0.3795720	-5.157066	0.0000003	0.0000298	ENSG00000182795.12	C1orf116	FC_P	C1orf116	-1.956457	0.0000003
1.249314e+02	-1.956181	0.4454745	-3.675773	0.0002371	0.0041939	ENSG00000147573.12	TRIM55	FC_P	TRIM55	-1.956181	0.0002371
1.018293e+01	1.954408	0.4715544	3.992185	0.0000655	0.0017047	ENSG00000152910.14	CNTNAP4	FC_P	CNTNAP4	1.954408	0.0000655
2.705269e+00	1.949760	0.4897405	3.900123	0.0000961	0.0022398	ENSG00000260701.1	RP11-449J10.1	FC_P	RP11.449J10.1	1.949760	0.0000961
7.808433e+00	1.947559	0.4231996	4.582713	0.0000046	0.0002557	ENSG00000261568.1	RP11-524C21.2	FC_P	RP11.524C21.2	1.947559	0.0000046
7.814688e+00	1.945145	0.3853301	5.015468	0.0000005	0.0000525	ENSG00000229854.1	RP11-524G24.2	FC_P	RP11.524G24.2	1.945145	0.0000005
7.076130e+00	1.944360	0.4473287	4.454981	0.0000084	0.0003904	ENSG00000064218.4	DMRT3	FC_P	DMRT3	1.944360	0.0000084
8.698383e+00	1.944283	0.4368485	4.634776	0.0000036	0.0002132	ENSG00000138675.12	FGF5	FC_P	FGF5	1.944283	0.0000036
2.513474e+01	1.942902	0.4418872	4.580138	0.0000046	0.0002573	ENSG00000004846.12	ABCB5	FC_P	ABCB5	1.942902	0.0000046
1.468510e+01	-1.941784	0.4206685	-4.607130	0.0000041	0.0002351	ENSG00000242640.1	RP11-302F12.1	FC_P	RP11.302F12.1	-1.941784	0.0000041
3.929205e+02	-1.941293	0.3599581	-5.425558	0.0000001	0.0000103	ENSG00000025423.7	HSD17B6	FC_P	HSD17B6	-1.941293	0.0000001
3.131499e+00	1.937358	0.4972667	3.946599	0.0000793	0.0019626	ENSG00000141668.5	CBLN2	FC_P	CBLN2	1.937358	0.0000793
1.463588e+02	1.937311	0.3849379	4.971849	0.0000007	0.0000622	ENSG00000169213.6	RAB3B	FC_P	RAB3B	1.937311	0.0000007
5.737157e+01	1.936138	0.2712039	7.153594	0.0000000	0.0000000	ENSG00000253811.1	CTD-2363C16.1	FC_P	CTD.2363C16.1	1.936138	0.0000000
2.407985e+01	1.935471	0.4831363	3.978951	0.0000692	0.0017730	ENSG00000267013.1	CTD-2171N6.1	FC_P	CTD.2171N6.1	1.935471	0.0000692
4.436683e+01	-1.935420	0.4814556	-4.042322	0.0000529	0.0014675	ENSG00000184735.5	DDX53	FC_P	DDX53	-1.935420	0.0000529
2.809458e+00	1.934997	0.4470258	4.243879	0.0000220	0.0007808	ENSG00000201623.1	RNU6-923P	FC_P	RNU6.923P	1.934997	0.0000220
1.070049e+02	1.933455	0.3862478	4.991336	0.0000006	0.0000577	ENSG00000230838.1	AC093850.2	FC_P	AC093850.2	1.933455	0.0000006
4.270714e+00	1.933268	0.4251884	4.502025	0.0000067	0.0003300	ENSG00000234323.1	RP11-308N19.1	FC_P	RP11.308N19.1	1.933268	0.0000067
8.320001e+00	-1.932171	0.4443281	-4.355509	0.0000133	0.0005402	ENSG00000206043.6	C18orf63	FC_P	C18orf63	-1.932171	0.0000133
5.109351e+02	1.931337	0.2875923	6.795427	0.0000000	0.0000000	ENSG00000075213.6	SEMA3A	FC_P	SEMA3A	1.931337	0.0000000
4.326193e+02	-1.930694	0.4451816	-4.322519	0.0000154	0.0006017	ENSG00000165186.9	PTCHD1	FC_P	PTCHD1	-1.930694	0.0000154
2.240881e+00	1.929764	0.4757118	4.055313	0.0000501	0.0014081	ENSG00000228595.1	PAICSP2	FC_P	PAICSP2	1.929764	0.0000501
3.316247e+00	1.926551	0.4865204	4.036202	0.0000543	0.0014975	ENSG00000250563.1	KNOP1P5	FC_P	KNOP1P5	1.926551	0.0000543
1.782811e+02	-1.926171	0.4756416	-4.146424	0.0000338	0.0010698	ENSG00000004848.6	ARX	FC_P	ARX	-1.926171	0.0000338
2.761094e+03	-1.922097	0.3656279	-5.259918	0.0000001	0.0000198	ENSG00000108551.4	RASD1	FC_P	RASD1	-1.922097	0.0000001
1.377451e+02	-1.921644	0.4366592	-4.383700	0.0000117	0.0004980	ENSG00000174473.11	GALNTL6	FC_P	GALNTL6	-1.921644	0.0000117
3.859033e+00	1.921099	0.4943122	4.165855	0.0000310	0.0010046	ENSG00000233569.1	RP11-500B12.1	FC_P	RP11.500B12.1	1.921099	0.0000310
7.266267e+01	1.918977	0.4379873	4.820666	0.0000014	0.0001095	ENSG00000124875.5	CXCL6	FC_P	CXCL6	1.918977	0.0000014
1.329358e+02	1.918573	0.4432469	4.415817	0.0000101	0.0004441	ENSG00000211658.2	IGLV3-27	FC_P	IGLV3.27	1.918573	0.0000101
1.416023e+02	1.917588	0.3531442	5.871664	0.0000000	0.0000016	ENSG00000249835.2	VCAN-AS1	FC_P	VCAN.AS1	1.917588	0.0000000
3.462151e+00	-1.915013	0.4676970	-4.177873	0.0000294	0.0009705	ENSG00000237964.3	AC068042.1	FC_P	AC068042.1	-1.915013	0.0000294
3.500752e+04	-1.912986	0.3227477	-5.932067	0.0000000	0.0000012	ENSG00000157765.7	SLC34A2	FC_P	SLC34A2	-1.912986	0.0000000
2.229606e+01	-1.911371	0.5031622	-5.794394	0.0000000	0.0000023	ENSG00000150201.10	FXYD4	FC_P	FXYD4	-1.911371	0.0000000
6.530839e+00	1.910733	0.4581066	4.200094	0.0000267	0.0009014	ENSG00000251443.1	RP11-113I22.1	FC_P	RP11.113I22.1	1.910733	0.0000267
2.607596e+00	1.907201	0.5038218	3.918417	0.0000891	0.0021329	ENSG00000218351.2	RPS3AP23	FC_P	RPS3AP23	1.907201	0.0000891
3.513745e+00	1.903397	0.4996928	3.710384	0.0002069	0.0037902	ENSG00000228358.1	AC113617.1	FC_P	AC113617.1	1.903397	0.0002069
2.639775e+00	1.903258	0.4983598	4.179773	0.0000292	0.0009667	ENSG00000229847.4	EMX2OS	FC_P	EMX2OS	1.903258	0.0000292
3.575969e+02	-1.902834	0.4493509	-4.220145	0.0000244	0.0008406	ENSG00000188089.9	PLA2G4E	FC_P	PLA2G4E	-1.902834	0.0000244
2.743970e+02	1.902335	0.3171507	5.999995	0.0000000	0.0000009	ENSG00000019549.4	SNAI2	FC_P	SNAI2	1.902335	0.0000000
3.850121e+00	1.899117	0.4194202	4.477174	0.0000076	0.0003622	ENSG00000259744.1	RP11-138H8.6	FC_P	RP11.138H8.6	1.899117	0.0000076
3.279456e+01	-1.896633	0.3783587	-4.976156	0.0000006	0.0000613	ENSG00000240541.2	TM4SF1-AS1	FC_P	TM4SF1.AS1	-1.896633	0.0000006
4.040697e+02	1.896492	0.2934100	6.552604	0.0000000	0.0000001	ENSG00000198523.5	PLN	FC_P	PLN	1.896492	0.0000000
7.678369e+00	1.890602	0.5036865	3.783855	0.0001544	0.0031109	ENSG00000113430.5	IRX4	FC_P	IRX4	1.890602	0.0001544
1.888745e+01	1.888862	0.3639993	5.368782	0.0000001	0.0000132	ENSG00000273264.1	RP11-131L23.2	FC_P	RP11.131L23.2	1.888862	0.0000001
1.531601e+01	1.887265	0.4119438	4.588180	0.0000045	0.0002524	ENSG00000225879.1	RP3-495K2.3	FC_P	RP3.495K2.3	1.887265	0.0000045
4.538285e+02	-1.886985	0.3256959	-5.711626	0.0000000	0.0000032	ENSG00000214456.4	PLIN5	FC_P	PLIN5	-1.886985	0.0000000
6.891955e+01	-1.886956	0.4418257	-4.295646	0.0000174	0.0006624	ENSG00000259541.1	RP11-778O17.4	FC_P	RP11.778O17.4	-1.886956	0.0000174
4.470125e+01	-1.886729	0.3369256	-5.627334	0.0000000	0.0000044	ENSG00000260637.1	RP11-46C24.5	FC_P	RP11.46C24.5	-1.886729	0.0000000
1.028215e+02	1.886690	0.3860519	5.355262	0.0000001	0.0000137	ENSG00000197614.6	MFAP5	FC_P	MFAP5	1.886690	0.0000001
3.838742e+00	1.885543	0.4494835	4.167049	0.0000309	0.0010028	ENSG00000251399.1	RP11-234K19.1	FC_P	RP11.234K19.1	1.885543	0.0000309
2.090004e+00	1.881998	0.4658007	3.831528	0.0001273	0.0027161	ENSG00000188269.4	OR7A5	FC_P	OR7A5	1.881998	0.0001273
1.412913e+03	1.881522	0.3320227	5.684098	0.0000000	0.0000035	ENSG00000272761.1	RP11-572C15.6	FC_P	RP11.572C15.6	1.881522	0.0000000
2.925340e+01	1.876569	0.2886119	6.483946	0.0000000	0.0000001	ENSG00000233821.1	ENOX1-AS1	FC_P	ENOX1.AS1	1.876569	0.0000000
1.196219e+01	1.874210	0.4037510	4.574067	0.0000048	0.0002618	ENSG00000249605.1	CTC-218H9.1	FC_P	CTC.218H9.1	1.874210	0.0000048
8.435522e+02	1.873890	0.4098625	4.426349	0.0000096	0.0004306	ENSG00000196611.4	MMP1	FC_P	MMP1	1.873890	0.0000096
4.952131e+01	1.873332	0.3886437	4.885633	0.0000010	0.0000857	ENSG00000138650.7	PCDH10	FC_P	PCDH10	1.873332	0.0000010
7.655277e+00	1.868010	0.4237700	4.382790	0.0000117	0.0004994	ENSG00000250433.1	CLSTN2-AS1	FC_P	CLSTN2.AS1	1.868010	0.0000117
2.068964e+00	1.867822	0.4684975	3.891090	0.0000998	0.0022984	ENSG00000265317.1	AC103740.1	FC_P	AC103740.1	1.867822	0.0000998
1.325839e+01	1.867179	0.3344891	5.552913	0.0000000	0.0000060	ENSG00000259432.1	RP11-37C7.2	FC_P	RP11.37C7.2	1.867179	0.0000000
6.008914e+00	1.866589	0.4724644	4.461921	0.0000081	0.0003812	ENSG00000262745.1	CTD-2377D24.8	FC_P	CTD.2377D24.8	1.866589	0.0000081
6.255828e+00	1.865339	0.4664870	3.715951	0.0002024	0.0037332	ENSG00000224547.1	AC023669.2	FC_P	AC023669.2	1.865339	0.0002024
9.559614e+00	1.863349	0.4143254	4.617952	0.0000039	0.0002245	ENSG00000259285.1	CTD-2330J20.2	FC_P	CTD.2330J20.2	1.863349	0.0000039
1.651715e+03	1.863270	0.2937023	6.332105	0.0000000	0.0000002	ENSG00000162692.6	VCAM1	FC_P	VCAM1	1.863270	0.0000000
1.442268e+01	1.861331	0.5032624	3.919997	0.0000885	0.0021221	ENSG00000081138.9	CDH7	FC_P	CDH7	1.861331	0.0000885
1.444545e+03	-1.858711	0.3347588	-5.424129	0.0000001	0.0000103	ENSG00000159228.8	CBR1	FC_P	CBR1	-1.858711	0.0000001
1.108393e+03	-1.858169	0.3212696	-5.814715	0.0000000	0.0000021	ENSG00000170561.8	IRX2	FC_P	IRX2	-1.858169	0.0000000
5.112319e+00	1.856368	0.4562803	3.913967	0.0000908	0.0021558	ENSG00000231098.1	AC008154.4	FC_P	AC008154.4	1.856368	0.0000908
1.415880e+01	-1.855826	0.3887564	-4.640612	0.0000035	0.0002090	ENSG00000259757.1	RP11-129I19.2	FC_P	RP11.129I19.2	-1.855826	0.0000035
3.794768e+00	1.854618	0.4995086	3.639918	0.0002727	0.0046276	ENSG00000227877.2	LINC00948	FC_P	LINC00948	1.854618	0.0002727
3.963479e+00	1.850253	0.3791200	4.743785	0.0000021	0.0001445	ENSG00000259831.1	LINC00567	FC_P	LINC00567	1.850253	0.0000021
2.015122e+01	1.849703	0.4836280	3.853250	0.0001166	0.0025570	ENSG00000265579.1	RP11-713C5.1	FC_P	RP11.713C5.1	1.849703	0.0001166
1.755826e+03	1.849416	0.3577140	5.103877	0.0000003	0.0000367	ENSG00000137809.12	ITGA11	FC_P	ITGA11	1.849416	0.0000003
1.940897e+03	1.849253	0.4307184	4.373599	0.0000122	0.0005100	ENSG00000099953.5	MMP11	FC_P	MMP11	1.849253	0.0000122
9.029697e+00	1.847624	0.3850832	4.777521	0.0000018	0.0001273	ENSG00000265711.1	AL049871.1	FC_P	AL049871.1	1.847624	0.0000018
1.504546e+01	-1.846350	0.4695844	-3.867184	0.0001101	0.0024701	ENSG00000248802.1	RP11-184M15.2	FC_P	RP11.184M15.2	-1.846350	0.0001101
9.961949e+00	1.845684	0.4070325	4.478564	0.0000075	0.0003604	ENSG00000228539.1	RP11-526K17.2	FC_P	RP11.526K17.2	1.845684	0.0000075
1.254532e+02	-1.843579	0.3873039	-4.936932	0.0000008	0.0000699	ENSG00000248738.2	RP11-87E22.2	FC_P	RP11.87E22.2	-1.843579	0.0000008
1.110985e+01	1.843537	0.3706264	4.992242	0.0000006	0.0000575	ENSG00000216022.1	AC068062.1	FC_P	AC068062.1	1.843537	0.0000006
3.891876e+02	-1.843498	0.3634675	-5.026368	0.0000005	0.0000501	ENSG00000188660.3	LINC00319	FC_P	LINC00319	-1.843498	0.0000005
1.080262e+01	1.843322	0.3913214	4.801942	0.0000016	0.0001168	ENSG00000257859.1	RP11-266E14.1	FC_P	RP11.266E14.1	1.843322	0.0000016
6.242904e+00	1.843059	0.4098198	4.473753	0.0000077	0.0003667	ENSG00000267712.1	RP11-456O19.4	FC_P	RP11.456O19.4	1.843059	0.0000077
2.030972e+01	1.842741	0.3072919	6.016472	0.0000000	0.0000008	ENSG00000253317.1	RP11-142A23.1	FC_P	RP11.142A23.1	1.842741	0.0000000
1.248205e+02	-1.840716	0.4360339	-4.505007	0.0000066	0.0003275	ENSG00000259104.2	PTCSC3	FC_P	PTCSC3	-1.840716	0.0000066
3.929601e+02	1.838617	0.3115213	5.884032	0.0000000	0.0000015	ENSG00000218336.3	TENM3	FC_P	TENM3	1.838617	0.0000000
3.568017e+00	1.837156	0.4912737	3.686863	0.0002270	0.0040574	ENSG00000260003.1	RP11-279O17.2	FC_P	RP11.279O17.2	1.837156	0.0002270
1.045953e+04	1.836608	0.3624108	5.033116	0.0000005	0.0000490	ENSG00000186340.10	THBS2	FC_P	THBS2	1.836608	0.0000005
4.969319e+00	1.836319	0.4716733	4.347364	0.0000138	0.0005571	ENSG00000235180.1	LINC00601	FC_P	LINC00601	1.836319	0.0000138
9.989617e+00	1.834229	0.4823893	3.510318	0.0004476	0.0065153	ENSG00000006128.7	TAC1	FC_P	TAC1	1.834229	0.0004476
8.021432e+02	1.832445	0.3029243	6.021063	0.0000000	0.0000008	ENSG00000104415.9	WISP1	FC_P	WISP1	1.832445	0.0000000
4.611380e+00	1.830308	0.4660805	3.815746	0.0001358	0.0028447	ENSG00000248266.1	RP11-402C9.1	FC_P	RP11.402C9.1	1.830308	0.0001358
1.311831e+01	1.827736	0.4668014	4.057162	0.0000497	0.0014012	ENSG00000242948.1	EPS15P1	FC_P	EPS15P1	1.827736	0.0000497
1.979341e+00	1.826577	0.4991542	3.479834	0.0005017	0.0070683	ENSG00000252489.1	RNU6-197P	FC_P	RNU6.197P	1.826577	0.0005017
1.367560e+02	1.826244	0.3951933	4.583482	0.0000046	0.0002551	ENSG00000170558.4	CDH2	FC_P	CDH2	1.826244	0.0000046
6.342260e+02	1.826214	0.4821043	3.933957	0.0000836	0.0020310	ENSG00000149948.9	HMGA2	FC_P	HMGA2	1.826214	0.0000836
3.292903e+01	1.825393	0.3216652	5.695764	0.0000000	0.0000034	ENSG00000102468.6	HTR2A	FC_P	HTR2A	1.825393	0.0000000
2.835073e+03	-1.824282	0.4936856	-3.756707	0.0001722	0.0033300	ENSG00000108602.13	ALDH3A1	FC_P	ALDH3A1	-1.824282	0.0001722
6.984923e+01	1.824197	0.3630195	4.946205	0.0000008	0.0000677	ENSG00000215208.3	KRT18P60	FC_P	KRT18P60	1.824197	0.0000008
3.626481e+01	1.821166	0.3036472	6.080619	0.0000000	0.0000007	ENSG00000238541.1	snoU13	FC_P	snoU13	1.821166	0.0000000
7.347680e+01	1.819621	0.3946379	4.617133	0.0000039	0.0002250	ENSG00000179603.13	GRM8	FC_P	GRM8	1.819621	0.0000039
7.170568e+02	1.817951	0.3931770	4.583700	0.0000046	0.0002551	ENSG00000211448.7	DIO2	FC_P	DIO2	1.817951	0.0000046
7.143719e+03	1.817894	0.3458244	5.209168	0.0000002	0.0000239	ENSG00000137573.9	SULF1	FC_P	SULF1	1.817894	0.0000002
3.719542e+00	1.815942	0.4806489	3.637742	0.0002750	0.0046542	ENSG00000237125.4	HAND2-AS1	FC_P	HAND2.AS1	1.815942	0.0002750
2.691385e+01	1.815781	0.3935111	4.679697	0.0000029	0.0001810	ENSG00000227658.1	AC005160.3	FC_P	AC005160.3	1.815781	0.0000029
1.538917e+01	1.815694	0.2787295	6.467849	0.0000000	0.0000001	ENSG00000240964.2	RN7SL751P	FC_P	RN7SL751P	1.815694	0.0000000
2.160741e+01	1.812958	0.4613600	3.861029	0.0001129	0.0025107	ENSG00000259439.1	RP11-89K21.1	FC_P	RP11.89K21.1	1.812958	0.0001129
4.571608e+01	1.812155	0.3378304	5.438269	0.0000001	0.0000097	ENSG00000253420.1	RP11-642D21.2	FC_P	RP11.642D21.2	1.812155	0.0000001
1.647838e+05	-1.810318	0.4551536	-3.968671	0.0000723	0.0018325	ENSG00000168878.12	SFTPB	FC_P	SFTPB	-1.810318	0.0000723
3.815895e+00	1.809861	0.4790291	4.423629	0.0000097	0.0004338	ENSG00000202142.1	SNORD114-18	FC_P	SNORD114.18	1.809861	0.0000097
2.820257e+01	-1.808811	0.3300758	-5.523611	0.0000000	0.0000067	ENSG00000221142.1	AC104405.1	FC_P	AC104405.1	-1.808811	0.0000000
9.943525e+00	1.808623	0.4360254	4.133527	0.0000357	0.0011184	ENSG00000266995.1	RP11-703I16.3	FC_P	RP11.703I16.3	1.808623	0.0000357
3.264893e+02	1.807010	0.3082886	5.803652	0.0000000	0.0000022	ENSG00000158258.11	CLSTN2	FC_P	CLSTN2	1.807010	0.0000000
5.942884e+01	1.806604	0.2966719	6.167175	0.0000000	0.0000005	ENSG00000267402.1	RP11-619L19.2	FC_P	RP11.619L19.2	1.806604	0.0000000
2.003728e+00	1.804986	0.4886280	3.347581	0.0008152	0.0100688	ENSG00000232554.4	RSU1P2	FC_P	RSU1P2	1.804986	0.0008152
8.350255e+00	1.801095	0.3864586	4.563933	0.0000050	0.0002711	ENSG00000270741.1	RP11-565F4.1	FC_P	RP11.565F4.1	1.801095	0.0000050
9.662791e+00	1.800270	0.3566951	4.950366	0.0000007	0.0000668	ENSG00000224594.2	RPL29P19	FC_P	RPL29P19	1.800270	0.0000007
9.935415e+01	-1.800008	0.3948549	-4.546206	0.0000055	0.0002863	ENSG00000220154.2	RP11-46B11.2	FC_P	RP11.46B11.2	-1.800008	0.0000055
8.320257e+00	-1.799055	0.4089774	-4.406004	0.0000105	0.0004604	ENSG00000162399.6	BSND	FC_P	BSND	-1.799055	0.0000105
2.657880e+00	1.797924	0.4552042	3.766389	0.0001656	0.0032425	ENSG00000249742.1	RP11-217E13.1	FC_P	RP11.217E13.1	1.797924	0.0001656
2.482570e+02	1.797803	0.3170427	5.686363	0.0000000	0.0000035	ENSG00000153993.9	SEMA3D	FC_P	SEMA3D	1.797803	0.0000000
2.648497e+00	1.797634	0.4937480	3.339395	0.0008396	0.0102791	ENSG00000155918.3	RAET1L	FC_P	RAET1L	1.797634	0.0008396
1.570973e+00	1.797111	0.5020129	3.439213	0.0005834	0.0079395	ENSG00000241956.5	CTC-340A15.2	FC_P	CTC.340A15.2	1.797111	0.0005834
2.754846e+00	1.797053	0.5012036	3.997905	0.0000639	0.0016773	ENSG00000270895.1	IGHG2	FC_P	IGHG2	1.797053	0.0000639
1.919613e+03	1.794996	0.2959683	6.060462	0.0000000	0.0000007	ENSG00000116132.7	PRRX1	FC_P	PRRX1	1.794996	0.0000000
5.681668e+00	1.793617	0.4616142	3.791081	0.0001500	0.0030453	ENSG00000162989.3	KCNJ3	FC_P	KCNJ3	1.793617	0.0001500
5.567918e+01	-1.790499	0.3877571	-4.713708	0.0000024	0.0001591	ENSG00000217644.4	RP4-803A2.1	FC_P	RP4.803A2.1	-1.790499	0.0000024
8.342677e+01	-1.788337	0.4014379	-4.570767	0.0000049	0.0002648	ENSG00000206557.5	TRIM71	FC_P	TRIM71	-1.788337	0.0000049
1.084285e+01	-1.787589	0.5032887	-3.656325	0.0002559	0.0044232	ENSG00000237937.1	AP000770.1	FC_P	AP000770.1	-1.787589	0.0002559
8.903716e+00	1.783274	0.3583748	4.873424	0.0000011	0.0000897	ENSG00000255342.1	RP11-762B21.5	FC_P	RP11.762B21.5	1.783274	0.0000011
3.913139e+01	1.783072	0.3410618	5.224709	0.0000002	0.0000226	ENSG00000253932.1	RP11-10C8.2	FC_P	RP11.10C8.2	1.783072	0.0000002
1.517124e+01	1.781751	0.4956366	4.091607	0.0000428	0.0012614	ENSG00000164651.12	SP8	FC_P	SP8	1.781751	0.0000428
3.557186e+03	-1.781722	0.4067889	-4.373915	0.0000122	0.0005100	ENSG00000142973.8	CYP4B1	FC_P	CYP4B1	-1.781722	0.0000122
2.161417e+03	-1.780842	0.4780996	-3.769554	0.0001635	0.0032134	ENSG00000021826.10	CPS1	FC_P	CPS1	-1.780842	0.0001635
1.823556e+01	1.779761	0.4094366	4.440473	0.0000090	0.0004101	ENSG00000261327.3	RP11-863P13.3	FC_P	RP11.863P13.3	1.779761	0.0000090
2.638314e+00	1.779180	0.4707500	3.683844	0.0002297	0.0040902	ENSG00000236332.1	AP001605.4	FC_P	AP001605.4	1.779180	0.0002297
1.564496e+02	-1.778362	0.3313549	-5.366630	0.0000001	0.0000132	ENSG00000185924.6	RTN4RL1	FC_P	RTN4RL1	-1.778362	0.0000001
5.696315e+01	1.777837	0.3825458	4.656142	0.0000032	0.0001970	ENSG00000268460.1	AC006262.6	FC_P	AC006262.6	1.777837	0.0000032
5.524237e+00	1.777824	0.4109280	4.267790	0.0000197	0.0007263	ENSG00000250732.1	RPEP1	FC_P	RPEP1	1.777824	0.0000197
9.312302e+01	1.776789	0.3454070	5.307232	0.0000001	0.0000168	ENSG00000248458.2	AL139147.1	FC_P	AL139147.1	1.776789	0.0000001
3.353394e+00	1.776164	0.4406577	3.979888	0.0000689	0.0017696	ENSG00000250619.1	CTD-2215L10.1	FC_P	CTD.2215L10.1	1.776164	0.0000689
7.352598e+00	1.775453	0.4488847	4.078764	0.0000453	0.0013085	ENSG00000267922.1	AC007193.6	FC_P	AC007193.6	1.775453	0.0000453
8.608565e+01	1.773444	0.2926017	6.242816	0.0000000	0.0000003	ENSG00000231132.1	RP11-40C11.2	FC_P	RP11.40C11.2	1.773444	0.0000000
2.147373e+00	1.772477	0.5014297	3.485362	0.0004915	0.0069841	ENSG00000227279.1	AC015933.2	FC_P	AC015933.2	1.772477	0.0004915
1.779810e+00	1.771243	0.4923118	3.551635	0.0003828	0.0058257	ENSG00000251958.1	RNU6-1102P	FC_P	RNU6.1102P	1.771243	0.0003828
7.339703e+00	-1.770624	0.4305965	-4.097197	0.0000418	0.0012390	ENSG00000264644.1	KRT18P8	FC_P	KRT18P8	-1.770624	0.0000418
3.721859e+03	-1.770593	0.2708463	-6.528394	0.0000000	0.0000001	ENSG00000008853.12	RHOBTB2	FC_P	RHOBTB2	-1.770593	0.0000000
6.042123e+00	1.769831	0.4233215	3.354960	0.0007938	0.0098666	ENSG00000252633.1	RN7SKP282	FC_P	RN7SKP282	1.769831	0.0007938
1.026744e+03	-1.765181	0.2955667	-5.949123	0.0000000	0.0000011	ENSG00000235109.3	ZSCAN31	FC_P	ZSCAN31	-1.765181	0.0000000
5.238940e+00	1.763965	0.4707602	3.571155	0.0003554	0.0055154	ENSG00000258537.1	FRMD6-AS2	FC_P	FRMD6.AS2	1.763965	0.0003554
7.657710e+01	1.763840	0.2914040	6.096226	0.0000000	0.0000007	ENSG00000235279.1	RP11-539E19.2	FC_P	RP11.539E19.2	1.763840	0.0000000
2.818653e+00	1.762171	0.4285156	4.128857	0.0000365	0.0011347	ENSG00000249951.1	RP11-554D13.1	FC_P	RP11.554D13.1	1.762171	0.0000365
1.627531e+03	-1.761945	0.3514317	-5.034449	0.0000005	0.0000490	ENSG00000146477.4	SLC22A3	FC_P	SLC22A3	-1.761945	0.0000005
4.009880e+00	-1.761739	0.4553428	-3.848519	0.0001188	0.0025963	ENSG00000253542.3	SDR16C6P	FC_P	SDR16C6P	-1.761739	0.0001188
1.344270e+02	1.761455	0.3330707	5.294090	0.0000001	0.0000175	ENSG00000226445.1	XXyac-YX65C7_A.2	FC_P	XXyac.YX65C7_A.2	1.761455	0.0000001
1.969578e+01	1.761081	0.4396561	4.286089	0.0000182	0.0006831	ENSG00000224394.1	GPC6-AS2	FC_P	GPC6.AS2	1.761081	0.0000182
6.815139e+00	1.759877	0.4007685	4.369362	0.0000125	0.0005156	ENSG00000233143.1	AC009492.1	FC_P	AC009492.1	1.759877	0.0000125
1.077705e+03	-1.759081	0.3930597	-4.488050	0.0000072	0.0003465	ENSG00000196208.9	GREB1	FC_P	GREB1	-1.759081	0.0000072
6.835484e+03	1.757915	0.3364630	5.200558	0.0000002	0.0000248	ENSG00000101825.7	MXRA5	FC_P	MXRA5	1.757915	0.0000002
3.049834e+00	1.757563	0.4525499	3.798534	0.0001456	0.0029923	ENSG00000146857.3	STRA8	FC_P	STRA8	1.757563	0.0001456
3.885605e+02	1.757208	0.3437352	5.090489	0.0000004	0.0000388	ENSG00000145536.11	ADAMTS16	FC_P	ADAMTS16	1.757208	0.0000004
8.134605e+01	-1.755613	0.4147815	-4.298870	0.0000172	0.0006547	ENSG00000253417.1	RP11-109J4.1	FC_P	RP11.109J4.1	-1.755613	0.0000172
3.249434e+00	1.755272	0.4398205	4.121194	0.0000377	0.0011626	ENSG00000112077.11	RHAG	FC_P	RHAG	1.755272	0.0000377
3.392295e+03	-1.751258	0.2708545	-6.462605	0.0000000	0.0000001	ENSG00000166347.14	CYB5A	FC_P	CYB5A	-1.751258	0.0000000
3.238072e+00	1.750675	0.4846275	4.202700	0.0000264	0.0008926	ENSG00000255921.1	RP11-662I13.2	FC_P	RP11.662I13.2	1.750675	0.0000264
2.244289e+01	1.749600	0.4917050	3.584423	0.0003378	0.0053376	ENSG00000270774.1	IGHV3-20	FC_P	IGHV3.20	1.749600	0.0003378
3.077626e+03	-1.747302	0.3004827	-5.832048	0.0000000	0.0000020	ENSG00000189221.5	MAOA	FC_P	MAOA	-1.747302	0.0000000
7.806226e+03	-1.745726	0.3752431	-4.673550	0.0000030	0.0001855	ENSG00000256612.3	CYP2B7P1	FC_P	CYP2B7P1	-1.745726	0.0000030
3.128155e+01	-1.744089	0.4454221	-4.040855	0.0000533	0.0014724	ENSG00000165606.4	DRGX	FC_P	DRGX	-1.744089	0.0000533
3.713868e+00	1.741460	0.4750713	3.820162	0.0001334	0.0028093	ENSG00000168505.6	GBX2	FC_P	GBX2	1.741460	0.0001334
1.158710e+01	1.740338	0.4007991	4.311085	0.0000162	0.0006272	ENSG00000228680.1	AC004692.4	FC_P	AC004692.4	1.740338	0.0000162
3.226922e+00	-1.739585	0.4892161	-3.588970	0.0003320	0.0052739	ENSG00000251448.1	RP11-71E19.2	FC_P	RP11.71E19.2	-1.739585	0.0003320
5.065059e+00	1.737941	0.4413217	4.107580	0.0000400	0.0012075	ENSG00000201247.1	SNORD114-13	FC_P	SNORD114.13	1.737941	0.0000400
1.309493e+02	1.737819	0.4403432	3.702355	0.0002136	0.0038783	ENSG00000211953.2	IGHV3-30	FC_P	IGHV3.30	1.737819	0.0002136
1.722992e+01	1.737542	0.4183394	4.292878	0.0000176	0.0006672	ENSG00000260862.1	RP11-22H5.2	FC_P	RP11.22H5.2	1.737542	0.0000176
4.594504e+00	1.737340	0.4028684	4.337499	0.0000144	0.0005728	ENSG00000252554.1	RNU6-861P	FC_P	RNU6.861P	1.737340	0.0000144
3.141878e+00	1.735202	0.5039400	3.584292	0.0003380	0.0053376	ENSG00000249645.1	RP11-552M14.1	FC_P	RP11.552M14.1	1.735202	0.0003380
2.717341e+00	1.735070	0.4775226	3.479057	0.0005032	0.0070809	ENSG00000253163.1	RP11-443C10.1	FC_P	RP11.443C10.1	1.735070	0.0005032
4.583071e+00	-1.734951	0.4946754	-3.532148	0.0004122	0.0061226	ENSG00000230455.2	BMS1P14	FC_P	BMS1P14	-1.734951	0.0004122
6.674702e+00	1.734000	0.5009139	3.660725	0.0002515	0.0043660	ENSG00000005073.5	HOXA11	FC_P	HOXA11	1.734000	0.0002515
2.227722e+01	1.727494	0.4946120	3.481107	0.0004993	0.0070480	ENSG00000083782.3	EPYC	FC_P	EPYC	1.727494	0.0004993
2.946642e+02	1.725061	0.3315463	5.274134	0.0000001	0.0000189	ENSG00000103742.7	IGDCC4	FC_P	IGDCC4	1.725061	0.0000001
7.264950e+01	1.724894	0.2903943	5.986208	0.0000000	0.0000009	ENSG00000253456.1	CTD-2363C16.2	FC_P	CTD.2363C16.2	1.724894	0.0000000
2.853363e+01	-1.723510	0.3914906	-4.374153	0.0000122	0.0005100	ENSG00000231445.1	TIMM8AP1	FC_P	TIMM8AP1	-1.723510	0.0000122
7.054640e+02	1.723444	0.3890670	4.371213	0.0000124	0.0005139	ENSG00000121904.13	CSMD2	FC_P	CSMD2	1.723444	0.0000124
1.124348e+01	1.723397	0.4289134	4.587694	0.0000045	0.0002526	ENSG00000201672.1	SNORD113-4	FC_P	SNORD113.4	1.723397	0.0000045
2.846222e+00	1.723223	0.4608331	3.674477	0.0002383	0.0042133	ENSG00000241361.4	SLC25A24P1	FC_P	SLC25A24P1	1.723223	0.0002383
6.664159e+00	1.721372	0.4141267	4.078008	0.0000454	0.0013108	ENSG00000254987.1	RP11-563P16.1	FC_P	RP11.563P16.1	1.721372	0.0000454
1.120814e+01	1.721066	0.4861875	3.855173	0.0001156	0.0025504	ENSG00000156920.6	GPR112	FC_P	GPR112	1.721066	0.0001156
5.696870e+00	1.720966	0.4684967	3.748275	0.0001781	0.0034228	ENSG00000260930.1	RP11-214L13.1	FC_P	RP11.214L13.1	1.720966	0.0001781
8.977399e+00	1.717826	0.3905446	4.448666	0.0000086	0.0003991	ENSG00000253576.1	GS1-5L10.1	FC_P	GS1.5L10.1	1.717826	0.0000086
1.799148e+02	-1.714262	0.4741490	-3.782287	0.0001554	0.0031111	ENSG00000111218.7	PRMT8	FC_P	PRMT8	-1.714262	0.0001554
1.006191e+01	1.712776	0.4446907	4.671401	0.0000030	0.0001869	ENSG00000212384.1	SNORD113-2	FC_P	SNORD113.2	1.712776	0.0000030
1.273362e+01	1.711156	0.4181515	4.757037	0.0000020	0.0001368	ENSG00000201700.2	SNORD113-3	FC_P	SNORD113.3	1.711156	0.0000020
3.770407e+02	-1.710940	0.4835295	-3.815568	0.0001359	0.0028447	ENSG00000271438.1	IGHD	FC_P	IGHD	-1.710940	0.0001359
3.045340e+00	1.710839	0.4887716	3.915376	0.0000903	0.0021510	ENSG00000167332.7	OR51E2	FC_P	OR51E2	1.710839	0.0000903
2.591618e+00	1.710819	0.4222754	3.975875	0.0000701	0.0017887	ENSG00000230448.1	LINC00276	FC_P	LINC00276	1.710819	0.0000701
1.986474e+01	-1.709945	0.4281417	-3.956063	0.0000762	0.0019096	ENSG00000229116.1	RP11-20J15.3	FC_P	RP11.20J15.3	-1.709945	0.0000762
3.109717e+02	-1.706707	0.4054978	-3.942988	0.0000805	0.0019797	ENSG00000166183.11	ASPG	FC_P	ASPG	-1.706707	0.0000805
1.576354e+01	-1.706622	0.4639239	-3.661835	0.0002504	0.0043552	ENSG00000261812.1	TUBB8P7	FC_P	TUBB8P7	-1.706622	0.0002504
1.064261e+01	1.705288	0.4057903	4.199506	0.0000267	0.0009027	ENSG00000250334.1	LINC00989	FC_P	LINC00989	1.705288	0.0000267
4.153042e+00	1.704267	0.4414941	3.815179	0.0001361	0.0028459	ENSG00000265488.1	AL359314.1	FC_P	AL359314.1	1.704267	0.0001361
6.500905e+01	-1.702902	0.4330442	-3.961436	0.0000745	0.0018788	ENSG00000138308.5	PLA2G12B	FC_P	PLA2G12B	-1.702902	0.0000745
8.755209e+00	1.699733	0.3792360	4.476941	0.0000076	0.0003622	ENSG00000257890.1	RP11-114F10.2	FC_P	RP11.114F10.2	1.699733	0.0000076
1.677386e+02	1.698680	0.3132325	5.534466	0.0000000	0.0000064	ENSG00000123610.3	TNFAIP6	FC_P	TNFAIP6	1.698680	0.0000000
7.233089e+00	1.698560	0.4535629	3.741394	0.0001830	0.0034929	ENSG00000122375.7	OPN4	FC_P	OPN4	1.698560	0.0001830
3.686073e+01	1.697261	0.3507925	4.948227	0.0000007	0.0000672	ENSG00000231756.1	RP11-183I6.2	FC_P	RP11.183I6.2	1.697261	0.0000007
1.288044e+01	1.696658	0.4315854	4.570784	0.0000049	0.0002648	ENSG00000251769.1	SNORD112	FC_P	SNORD112	1.696658	0.0000049
1.214460e+01	1.696157	0.3942866	4.232965	0.0000231	0.0008059	ENSG00000221390.1	MIR1295A	FC_P	MIR1295A	1.696157	0.0000231
4.212392e+00	1.695746	0.4083831	4.045704	0.0000522	0.0014530	ENSG00000222374.1	AC022021.1	FC_P	AC022021.1	1.695746	0.0000522
3.748422e+01	-1.692764	0.3817577	-4.528715	0.0000059	0.0003036	ENSG00000253142.1	RP11-87E22.1	FC_P	RP11.87E22.1	-1.692764	0.0000059
7.331320e+00	1.691339	0.3609108	4.625328	0.0000037	0.0002194	ENSG00000260089.2	ADAM3B	FC_P	ADAM3B	1.691339	0.0000037
1.150643e+02	-1.690459	0.3564659	-4.725064	0.0000023	0.0001526	ENSG00000188883.4	KLRG2	FC_P	KLRG2	-1.690459	0.0000023
9.490512e+00	1.688798	0.4098432	4.318531	0.0000157	0.0006095	ENSG00000250624.1	RP11-93M12.1	FC_P	RP11.93M12.1	1.688798	0.0000157
1.882547e+00	1.687788	0.4580852	3.649803	0.0002624	0.0045101	ENSG00000220377.1	RP1-152L7.3	FC_P	RP1.152L7.3	1.687788	0.0002624
2.043331e+00	1.687032	0.4960404	3.374247	0.0007402	0.0093792	ENSG00000261319.1	RP11-279O17.1	FC_P	RP11.279O17.1	1.687032	0.0007402
4.635228e+01	1.686691	0.3746529	4.643971	0.0000034	0.0002066	ENSG00000250320.1	CTD-2269F5.1	FC_P	CTD.2269F5.1	1.686691	0.0000034
1.368423e+02	1.686312	0.4816643	4.256783	0.0000207	0.0007487	ENSG00000270376.1	IGHV2-70	FC_P	IGHV2.70	1.686312	0.0000207
3.603167e+01	1.685715	0.4531422	3.982086	0.0000683	0.0017569	ENSG00000255745.1	RP11-625L16.1	FC_P	RP11.625L16.1	1.685715	0.0000683
2.299126e+01	-1.685193	0.4344342	-3.739685	0.0001843	0.0035079	ENSG00000249335.1	CTC-340D7.1	FC_P	CTC.340D7.1	-1.685193	0.0001843
3.242657e+01	1.683446	0.3881102	4.274304	0.0000192	0.0007117	ENSG00000109061.9	MYH1	FC_P	MYH1	1.683446	0.0000192
3.699219e+02	1.682675	0.3499383	4.802677	0.0000016	0.0001166	ENSG00000160161.5	CILP2	FC_P	CILP2	1.682675	0.0000016
3.690583e+00	1.682483	0.4593832	4.130808	0.0000361	0.0011289	ENSG00000199942.1	SNORD114-19	FC_P	SNORD114.19	1.682483	0.0000361
2.253704e+00	1.681750	0.4637245	3.636181	0.0002767	0.0046720	ENSG00000219284.2	RP11-151M7.1	FC_P	RP11.151M7.1	1.681750	0.0002767
1.568466e+02	1.681620	0.4717930	3.590660	0.0003298	0.0052511	ENSG00000166342.14	NETO1	FC_P	NETO1	1.681620	0.0003298
3.005680e+03	-1.681569	0.3849861	-4.396263	0.0000110	0.0004760	ENSG00000124107.5	SLPI	FC_P	SLPI	-1.681569	0.0000110
4.801677e+00	1.680324	0.4272192	4.076063	0.0000458	0.0013188	ENSG00000253370.2	CTB-56J15.1	FC_P	CTB.56J15.1	1.680324	0.0000458
1.422721e+01	1.678325	0.4594808	3.642892	0.0002696	0.0045972	ENSG00000226981.2	ABHD17AP6	FC_P	ABHD17AP6	1.678325	0.0002696
3.121629e+01	1.677527	0.3595002	4.780071	0.0000018	0.0001260	ENSG00000213170.3	RP11-81B10.2	FC_P	RP11.81B10.2	1.677527	0.0000018
6.063667e+00	1.677017	0.4901524	3.765344	0.0001663	0.0032455	ENSG00000260289.1	CTD-2535I10.1	FC_P	CTD.2535I10.1	1.677017	0.0001663
3.065246e+00	1.676883	0.4211836	3.918313	0.0000892	0.0021329	ENSG00000205562.1	RP11-497E19.1	FC_P	RP11.497E19.1	1.676883	0.0000892
1.443259e+02	1.676816	0.3425096	4.910810	0.0000009	0.0000777	ENSG00000248222.1	CTB-174D11.1	FC_P	CTB.174D11.1	1.676816	0.0000009
1.927163e+01	1.676480	0.3205927	5.272745	0.0000001	0.0000189	ENSG00000251001.1	CTD-2193P3.1	FC_P	CTD.2193P3.1	1.676480	0.0000001
2.218301e+02	1.676334	0.2576934	6.497810	0.0000000	0.0000001	ENSG00000180139.10	ACTA2-AS1	FC_P	ACTA2.AS1	1.676334	0.0000000
1.692791e+03	1.676310	0.3111537	5.393809	0.0000001	0.0000119	ENSG00000206538.3	VGLL3	FC_P	VGLL3	1.676310	0.0000001
9.134812e+00	1.675022	0.3954264	4.217735	0.0000247	0.0008474	ENSG00000226771.1	AP001136.2	FC_P	AP001136.2	1.675022	0.0000247
6.096797e+02	-1.674763	0.3461731	-4.847954	0.0000012	0.0000992	ENSG00000125872.7	LRRN4	FC_P	LRRN4	-1.674763	0.0000012
3.599143e+00	1.674137	0.4601509	3.602764	0.0003149	0.0051073	ENSG00000225269.2	LINC00705	FC_P	LINC00705	1.674137	0.0003149
1.019923e+02	1.672974	0.2951710	5.699350	0.0000000	0.0000034	ENSG00000256721.1	CACNA1C-IT3	FC_P	CACNA1C.IT3	1.672974	0.0000000
2.108059e+01	1.672690	0.3454285	4.889039	0.0000010	0.0000845	ENSG00000254163.1	CTC-340I23.2	FC_P	CTC.340I23.2	1.672690	0.0000010
5.874726e+01	-1.672676	0.4134888	-4.000737	0.0000631	0.0016650	ENSG00000255692.1	RP1-127H14.3	FC_P	RP1.127H14.3	-1.672676	0.0000631
1.847306e+01	1.672084	0.3127175	5.327118	0.0000001	0.0000155	ENSG00000227992.1	AC108463.2	FC_P	AC108463.2	1.672084	0.0000001
1.720357e+03	1.671670	0.3234195	5.127347	0.0000003	0.0000336	ENSG00000151388.6	ADAMTS12	FC_P	ADAMTS12	1.671670	0.0000003
2.787060e+02	-1.670001	0.4210494	-3.782948	0.0001550	0.0031111	ENSG00000171658.4	RP11-443P15.2	FC_P	RP11.443P15.2	-1.670001	0.0001550
4.742276e+02	-1.669823	0.2943212	-5.737235	0.0000000	0.0000029	ENSG00000183840.5	GPR39	FC_P	GPR39	-1.669823	0.0000000
2.528643e+00	1.669774	0.4903197	3.425041	0.0006147	0.0082407	ENSG00000249203.1	RP11-473L15.3	FC_P	RP11.473L15.3	1.669774	0.0006147
7.373028e+00	1.668956	0.3597246	4.653484	0.0000033	0.0001986	ENSG00000207072.1	RNU6-39P	FC_P	RNU6.39P	1.668956	0.0000033
6.809776e+00	-1.668201	0.5034580	-3.448746	0.0005632	0.0077162	ENSG00000213873.4	RP11-678D18.1	FC_P	RP11.678D18.1	-1.668201	0.0005632
3.388343e+01	-1.667613	0.4746535	-3.564215	0.0003649	0.0056229	ENSG00000266968.1	RP11-116O18.1	FC_P	RP11.116O18.1	-1.667613	0.0003649
4.604331e+03	-1.666729	0.3515916	-4.690691	0.0000027	0.0001735	ENSG00000165272.10	AQP3	FC_P	AQP3	-1.666729	0.0000027
1.591994e+02	1.666544	0.3005773	5.642427	0.0000000	0.0000041	ENSG00000230630.1	DNM3OS	FC_P	DNM3OS	1.666544	0.0000000
3.178982e+02	-1.664680	0.3998612	-4.466797	0.0000079	0.0003760	ENSG00000259974.2	LINC00261	FC_P	LINC00261	-1.664680	0.0000079
4.539391e+01	-1.663113	0.3600873	-4.619832	0.0000038	0.0002232	ENSG00000264175.1	MIR3189	FC_P	MIR3189	-1.663113	0.0000038
1.970363e+01	1.662253	0.2930578	5.657718	0.0000000	0.0000039	ENSG00000205644.5	CTD-2375G15.1	FC_P	CTD.2375G15.1	1.662253	0.0000000
4.214507e+01	-1.661806	0.3691408	-4.381984	0.0000118	0.0004994	ENSG00000229196.3	RP11-775D22.2	FC_P	RP11.775D22.2	-1.661806	0.0000118
2.571122e+00	1.661390	0.4528802	3.949189	0.0000784	0.0019488	ENSG00000201392.1	RNU6-1078P	FC_P	RNU6.1078P	1.661390	0.0000784
5.551552e+01	-1.661031	0.3818427	-4.407712	0.0000104	0.0004573	ENSG00000267385.1	CTB-50L17.14	FC_P	CTB.50L17.14	-1.661031	0.0000104
5.707860e+00	1.660252	0.3664008	4.475672	0.0000076	0.0003639	ENSG00000240752.1	RP11-588D3.1	FC_P	RP11.588D3.1	1.660252	0.0000076
1.929295e+01	1.659747	0.4336823	3.853847	0.0001163	0.0025538	ENSG00000271127.1	LL22NC03-N64E9.1	FC_P	LL22NC03.N64E9.1	1.659747	0.0001163
1.299068e+03	1.659023	0.3431725	4.832928	0.0000013	0.0001041	ENSG00000078098.9	FAP	FC_P	FAP	1.659023	0.0000013
2.113373e+01	1.657448	0.3663388	4.524305	0.0000061	0.0003074	ENSG00000232046.2	AC007392.3	FC_P	AC007392.3	1.657448	0.0000061
3.682418e+03	-1.656926	0.4293335	-4.280046	0.0000187	0.0006979	ENSG00000123838.6	C4BPA	FC_P	C4BPA	-1.656926	0.0000187
1.961750e+03	-1.656846	0.2724524	-6.055110	0.0000000	0.0000007	ENSG00000170412.12	GPRC5C	FC_P	GPRC5C	-1.656846	0.0000000
5.821285e+01	-1.656214	0.4125203	-4.091373	0.0000429	0.0012617	ENSG00000225154.2	RP11-184J23.2	FC_P	RP11.184J23.2	-1.656214	0.0000429
6.834894e+00	1.655078	0.3790794	4.349797	0.0000136	0.0005521	ENSG00000270313.1	CTC-786C10.2	FC_P	CTC.786C10.2	1.655078	0.0000136
1.395274e+01	-1.654845	0.2983264	-5.555736	0.0000000	0.0000060	ENSG00000262667.1	OCLN	FC_P	OCLN	-1.654845	0.0000000
9.628362e+00	1.653401	0.3286015	4.977944	0.0000006	0.0000612	ENSG00000248927.1	CTD-2334D19.1	FC_P	CTD.2334D19.1	1.653401	0.0000006
5.614794e+01	1.653202	0.2756435	6.016516	0.0000000	0.0000008	ENSG00000259532.1	RP11-138H8.2	FC_P	RP11.138H8.2	1.653202	0.0000000
9.970312e+00	1.652759	0.4459769	3.789764	0.0001508	0.0030582	ENSG00000228213.1	NLGN1-AS1	FC_P	NLGN1.AS1	1.652759	0.0001508
4.872993e+01	-1.651902	0.4266708	-3.849677	0.0001183	0.0025871	ENSG00000201464.1	Y_RNA	FC_P	Y_RNA	-1.651902	0.0001183
5.328449e+01	1.651139	0.3025023	5.487438	0.0000000	0.0000078	ENSG00000256120.1	RP11-778H2.1	FC_P	RP11.778H2.1	1.651139	0.0000000
9.687654e+00	-1.650964	0.4624245	-3.714618	0.0002035	0.0037437	ENSG00000255007.1	CTD-2589M5.4	FC_P	CTD.2589M5.4	-1.650964	0.0002035
1.322228e+01	1.650127	0.3739056	4.616906	0.0000039	0.0002250	ENSG00000237136.2	C4orf51	FC_P	C4orf51	1.650127	0.0000039
8.209060e+00	1.648654	0.3132615	5.223742	0.0000002	0.0000227	ENSG00000258452.1	RP11-757H14.2	FC_P	RP11.757H14.2	1.648654	0.0000002
1.164425e+01	1.648498	0.5037396	3.386285	0.0007085	0.0090928	ENSG00000270676.1	IGHV3-13	FC_P	IGHV3.13	1.648498	0.0007085
3.420473e+02	-1.647703	0.2824654	-5.803523	0.0000000	0.0000022	ENSG00000177191.2	B3GNT8	FC_P	B3GNT8	-1.647703	0.0000000
2.721026e+01	-1.647405	0.4297894	-3.873691	0.0001072	0.0024180	ENSG00000228044.2	RP4-781K5.4	FC_P	RP4.781K5.4	-1.647405	0.0001072
8.220842e+01	-1.647290	0.4585197	-3.821195	0.0001328	0.0028007	ENSG00000163283.6	ALPP	FC_P	ALPP	-1.647290	0.0001328
7.147183e+02	1.646763	0.3425527	4.879208	0.0000011	0.0000874	ENSG00000198734.6	F5	FC_P	F5	1.646763	0.0000011
7.823609e+00	-1.645437	0.4661637	-3.502874	0.0004603	0.0066563	ENSG00000168703.5	WFDC12	FC_P	WFDC12	-1.645437	0.0004603
1.467507e+01	1.644959	0.3712618	4.820020	0.0000014	0.0001095	ENSG00000216067.1	AC104457.1	FC_P	AC104457.1	1.644959	0.0000014
7.872388e+01	1.644792	0.4027169	4.666235	0.0000031	0.0001897	ENSG00000271417.1	RP11-909M7.3	FC_P	RP11.909M7.3	1.644792	0.0000031
6.282074e+00	1.643740	0.4045880	4.072541	0.0000465	0.0013338	ENSG00000241261.1	RPL17P19	FC_P	RPL17P19	1.643740	0.0000465
4.857985e+02	-1.643665	0.3676528	-4.423281	0.0000097	0.0004338	ENSG00000183250.7	C21orf67	FC_P	C21orf67	-1.643665	0.0000097
4.037609e+03	-1.643052	0.2996608	-5.457769	0.0000000	0.0000088	ENSG00000143416.16	SELENBP1	FC_P	SELENBP1	-1.643052	0.0000000
1.046089e+02	1.642951	0.4799178	3.490915	0.0004814	0.0068923	ENSG00000270452.1	IGHV1-2	FC_P	IGHV1.2	1.642951	0.0004814
2.588702e+02	-1.641411	0.3153709	-5.195820	0.0000002	0.0000252	ENSG00000127578.6	WFIKKN1	FC_P	WFIKKN1	-1.641411	0.0000002
2.514740e+01	-1.640619	0.3949595	-4.131420	0.0000361	0.0011269	ENSG00000262445.3	CTD-2545H1.2	FC_P	CTD.2545H1.2	-1.640619	0.0000361
2.715851e+00	1.638792	0.4215474	3.831697	0.0001273	0.0027158	ENSG00000237410.1	AP001092.4	FC_P	AP001092.4	1.638792	0.0001273
2.128693e+02	1.637860	0.3650919	4.576550	0.0000047	0.0002614	ENSG00000157766.11	ACAN	FC_P	ACAN	1.637860	0.0000047
1.401118e+01	1.635466	0.4281480	3.855441	0.0001155	0.0025491	ENSG00000259477.1	RP11-86K22.1	FC_P	RP11.86K22.1	1.635466	0.0001155
1.448363e+02	1.635207	0.3139962	5.251147	0.0000002	0.0000204	ENSG00000256025.1	CACNA1C-AS4	FC_P	CACNA1C.AS4	1.635207	0.0000002
3.392445e+00	1.635034	0.4614163	3.514998	0.0004398	0.0064249	ENSG00000227249.1	AC000374.1	FC_P	AC000374.1	1.635034	0.0004398
3.757773e+01	1.634748	0.3741406	4.368889	0.0000125	0.0005160	ENSG00000165966.10	PDZRN4	FC_P	PDZRN4	1.634748	0.0000125
1.189907e+03	1.633606	0.2841064	5.750803	0.0000000	0.0000028	ENSG00000122870.7	BICC1	FC_P	BICC1	1.633606	0.0000000
1.854304e+01	1.633506	0.3511225	4.758574	0.0000019	0.0001362	ENSG00000113600.6	C9	FC_P	C9	1.633506	0.0000019
1.272466e+01	1.633494	0.4477730	4.243576	0.0000220	0.0007811	ENSG00000202048.1	SNORD114-20	FC_P	SNORD114.20	1.633494	0.0000220
7.428657e+01	1.633396	0.4231504	3.874765	0.0001067	0.0024102	ENSG00000118729.10	CASQ2	FC_P	CASQ2	1.633396	0.0001067
2.263119e+01	1.632663	0.4123531	4.110185	0.0000395	0.0011988	ENSG00000236520.2	GPC6-AS1	FC_P	GPC6.AS1	1.632663	0.0000395
1.639718e+01	-1.632586	0.4506984	-3.780382	0.0001566	0.0031235	ENSG00000254391.1	CTC-529G1.1	FC_P	CTC.529G1.1	-1.632586	0.0001566
4.209170e+00	1.632198	0.4576349	3.445887	0.0005692	0.0077797	ENSG00000259339.2	TGIF1P1	FC_P	TGIF1P1	1.632198	0.0005692
1.817261e+01	1.631999	0.4011682	4.028860	0.0000560	0.0015260	ENSG00000228294.2	BMS1P17	FC_P	BMS1P17	1.631999	0.0000560
1.027529e+04	1.631701	0.3682423	4.462262	0.0000081	0.0003812	ENSG00000133110.10	POSTN	FC_P	POSTN	1.631701	0.0000081
3.062835e+00	1.631115	0.4478729	3.911231	0.0000918	0.0021743	ENSG00000200612.1	SNORD114-25	FC_P	SNORD114.25	1.631115	0.0000918
7.208717e+01	1.629978	0.4169326	3.869779	0.0001089	0.0024483	ENSG00000145794.12	MEGF10	FC_P	MEGF10	1.629978	0.0001089
1.190512e+03	1.628167	0.3093928	5.246381	0.0000002	0.0000206	ENSG00000154096.9	THY1	FC_P	THY1	1.628167	0.0000002
1.037636e+01	-1.627288	0.4681934	-3.314588	0.0009178	0.0109519	ENSG00000140798.11	ABCC12	FC_P	ABCC12	-1.627288	0.0009178
1.821993e+01	-1.627033	0.4130323	-3.882317	0.0001035	0.0023593	ENSG00000268287.1	CTB-60B18.18	FC_P	CTB.60B18.18	-1.627033	0.0001035
1.964662e+00	1.626629	0.4797149	3.500087	0.0004651	0.0067186	ENSG00000259914.1	RP11-298D21.2	FC_P	RP11.298D21.2	1.626629	0.0004651
1.316847e+03	-1.625940	0.2695341	-6.012677	0.0000000	0.0000009	ENSG00000179178.6	TMEM125	FC_P	TMEM125	-1.625940	0.0000000
7.964064e+01	-1.625455	0.4143210	-3.908064	0.0000930	0.0021975	ENSG00000272825.1	LL21NC02-1C16.2	FC_P	LL21NC02.1C16.2	-1.625455	0.0000930
4.997318e+00	1.623237	0.4215481	3.782652	0.0001552	0.0031111	ENSG00000139330.5	KERA	FC_P	KERA	1.623237	0.0001552
2.285976e+01	1.622604	0.4310883	3.880881	0.0001041	0.0023704	ENSG00000260585.1	RP13-192B19.2	FC_P	RP13.192B19.2	1.622604	0.0001041
8.589867e+02	1.622016	0.3333133	4.894508	0.0000010	0.0000827	ENSG00000017427.11	IGF1	FC_P	IGF1	1.622016	0.0000010
6.297236e+00	1.621233	0.4144384	3.851285	0.0001175	0.0025720	ENSG00000258375.2	RP11-617J18.1	FC_P	RP11.617J18.1	1.621233	0.0001175
6.412332e+00	1.621049	0.4014885	4.008890	0.0000610	0.0016282	ENSG00000186148.7	AC013271.3	FC_P	AC013271.3	1.621049	0.0000610
1.393257e+03	-1.620512	0.3278742	-5.068168	0.0000004	0.0000425	ENSG00000132698.9	RAB25	FC_P	RAB25	-1.620512	0.0000004
4.729167e+00	1.619908	0.4766588	3.403198	0.0006660	0.0087258	ENSG00000264238.1	AL590084.1	FC_P	AL590084.1	1.619908	0.0006660
1.127420e+02	1.618865	0.4654099	4.328758	0.0000150	0.0005892	ENSG00000198643.2	FAM3D	FC_P	FAM3D	1.618865	0.0000150
1.585805e+02	1.618651	0.2813431	5.709057	0.0000000	0.0000033	ENSG00000197927.8	C2orf27A	FC_P	C2orf27A	1.618651	0.0000000
1.586418e+01	1.616934	0.4715240	3.586058	0.0003357	0.0053128	ENSG00000248329.1	RP11-366M4.3	FC_P	RP11.366M4.3	1.616934	0.0003357
6.747180e+00	1.616011	0.5013156	3.774371	0.0001604	0.0031746	ENSG00000270315.1	IGHV3-43	FC_P	IGHV3.43	1.616011	0.0001604
3.249869e+00	1.615373	0.4070513	3.876464	0.0001060	0.0024021	ENSG00000265986.1	MIR4735	FC_P	MIR4735	1.615373	0.0001060
5.517541e+00	1.614728	0.4493444	4.149566	0.0000333	0.0010588	ENSG00000201950.1	SNORD113-9	FC_P	SNORD113.9	1.614728	0.0000333
2.499874e+01	1.614705	0.3621040	4.409226	0.0000104	0.0004546	ENSG00000254710.1	CTD-2216M2.1	FC_P	CTD.2216M2.1	1.614705	0.0000104
1.414925e+01	1.613417	0.3563989	4.527494	0.0000060	0.0003045	ENSG00000263952.1	RP11-513M1.1	FC_P	RP11.513M1.1	1.613417	0.0000060
3.859166e+01	-1.611508	0.3720711	-4.338645	0.0000143	0.0005727	ENSG00000228133.2	AC099684.1	FC_P	AC099684.1	-1.611508	0.0000143
7.616627e+00	1.609991	0.3811297	4.372100	0.0000123	0.0005124	ENSG00000237742.2	RP11-624M8.1	FC_P	RP11.624M8.1	1.609991	0.0000123
8.983577e+01	1.609125	0.3162764	5.093682	0.0000004	0.0000386	ENSG00000233098.4	RP11-344E13.3	FC_P	RP11.344E13.3	1.609125	0.0000004
5.603944e+00	1.608169	0.4598951	3.492484	0.0004786	0.0068601	ENSG00000226409.1	RP11-735G4.1	FC_P	RP11.735G4.1	1.608169	0.0004786
9.783900e+01	1.606016	0.3373223	4.782751	0.0000017	0.0001253	ENSG00000262655.2	SPON1	FC_P	SPON1	1.606016	0.0000017
4.803181e+00	1.603728	0.3649500	4.315082	0.0000160	0.0006172	ENSG00000221262.1	AC005159.1	FC_P	AC005159.1	1.603728	0.0000160
6.103595e+02	1.603298	0.3063551	5.220900	0.0000002	0.0000229	ENSG00000135919.8	SERPINE2	FC_P	SERPINE2	1.603298	0.0000002
4.419630e+00	1.602917	0.4775037	3.494734	0.0004745	0.0068207	ENSG00000204019.4	CXorf61	FC_P	CXorf61	1.602917	0.0004745
1.296048e+02	-1.601855	0.3710943	-4.107691	0.0000400	0.0012075	ENSG00000174808.7	BTC	FC_P	BTC	-1.601855	0.0000400
4.636383e+02	-1.601505	0.3428215	-4.732906	0.0000022	0.0001489	ENSG00000125798.10	FOXA2	FC_P	FOXA2	-1.601505	0.0000022
1.918860e+02	1.601493	0.4188073	3.859740	0.0001135	0.0025180	ENSG00000262406.2	MMP12	FC_P	MMP12	1.601493	0.0001135
8.203028e+00	-1.601447	0.4661254	-3.425978	0.0006126	0.0082273	ENSG00000223678.1	RP11-311H10.4	FC_P	RP11.311H10.4	-1.601447	0.0006126
1.477257e+02	-1.600894	0.3702742	-4.309753	0.0000163	0.0006297	ENSG00000158055.11	GRHL3	FC_P	GRHL3	-1.600894	0.0000163
3.391763e+01	1.600394	0.3405005	4.999269	0.0000006	0.0000562	ENSG00000238482.1	RNU6-1208P	FC_P	RNU6.1208P	1.600394	0.0000006
1.231434e+01	1.600069	0.3635891	4.492337	0.0000070	0.0003411	ENSG00000264434.1	CTD-2006O16.2	FC_P	CTD.2006O16.2	1.600069	0.0000070
2.117291e+03	-1.600029	0.3687682	-4.333816	0.0000147	0.0005788	ENSG00000007402.7	CACNA2D2	FC_P	CACNA2D2	-1.600029	0.0000147
2.991140e+00	1.599936	0.4190721	3.735257	0.0001875	0.0035486	ENSG00000248816.1	RP11-18D7.3	FC_P	RP11.18D7.3	1.599936	0.0001875
2.857604e+02	-1.599281	0.4394695	-3.607200	0.0003095	0.0050404	ENSG00000248608.2	RP11-206P5.2	FC_P	RP11.206P5.2	-1.599281	0.0003095
1.964453e+01	-1.598866	0.3879674	-4.097682	0.0000417	0.0012390	ENSG00000250237.1	CTC-498J12.1	FC_P	CTC.498J12.1	-1.598866	0.0000417
4.403595e+02	1.597764	0.3355566	4.773739	0.0000018	0.0001288	ENSG00000165474.5	GJB2	FC_P	GJB2	1.597764	0.0000018
3.968699e+01	-1.596712	0.4429079	-3.632977	0.0002802	0.0047135	ENSG00000249320.1	RP11-206P5.1	FC_P	RP11.206P5.1	-1.596712	0.0002802
3.707875e+02	1.595800	0.3308604	4.751552	0.0000020	0.0001395	ENSG00000086991.8	NOX4	FC_P	NOX4	1.595800	0.0000020
2.839287e+00	1.594618	0.4460114	3.521209	0.0004296	0.0063171	ENSG00000253449.1	CTC-436K13.6	FC_P	CTC.436K13.6	1.594618	0.0004296
2.668680e+00	-1.593760	0.4463049	-3.745418	0.0001801	0.0034514	ENSG00000164334.11	FAM170A	FC_P	FAM170A	-1.593760	0.0001801
1.191271e+01	1.593307	0.4508865	3.627543	0.0002861	0.0047774	ENSG00000183760.6	PAPL	FC_P	PAPL	1.593307	0.0002861
1.251600e+04	1.592104	0.3291507	4.930787	0.0000008	0.0000718	ENSG00000139329.4	LUM	FC_P	LUM	1.592104	0.0000008
2.931038e+02	-1.590254	0.3930584	-4.074277	0.0000462	0.0013263	ENSG00000251532.1	CTD-2245E15.3	FC_P	CTD.2245E15.3	-1.590254	0.0000462
2.071728e+00	1.590163	0.5011137	3.377130	0.0007325	0.0093203	ENSG00000238571.1	snoU13	FC_P	snoU13.2	1.590163	0.0007325
1.686261e+02	1.588729	0.3913418	4.716582	0.0000024	0.0001577	ENSG00000225746.4	AL132709.5	FC_P	AL132709.5	1.588729	0.0000024
2.387718e+00	1.587318	0.5031429	3.751161	0.0001760	0.0033889	ENSG00000237849.1	NFYAP1	FC_P	NFYAP1	1.587318	0.0001760
2.405490e+01	1.585390	0.3458736	4.686538	0.0000028	0.0001756	ENSG00000266591.1	AC022537.1	FC_P	AC022537.1	1.585390	0.0000028
4.819585e+01	1.583380	0.3856375	4.090496	0.0000430	0.0012645	ENSG00000237070.1	AC005550.3	FC_P	AC005550.3	1.583380	0.0000430
3.346199e+01	1.582586	0.2636356	5.987203	0.0000000	0.0000009	ENSG00000201176.1	RNU6-853P	FC_P	RNU6.853P	1.582586	0.0000000
1.290328e+01	-1.581133	0.4110849	-3.858882	0.0001139	0.0025209	ENSG00000224940.4	PRRT4	FC_P	PRRT4	-1.581133	0.0001139
7.351937e+00	1.581095	0.3324165	4.784331	0.0000017	0.0001248	ENSG00000215835.2	RP11-9L18.2	FC_P	RP11.9L18.2	1.581095	0.0000017
2.908785e+00	1.580678	0.4830833	3.400015	0.0006738	0.0088004	ENSG00000230787.1	PSAT1P3	FC_P	PSAT1P3	1.580678	0.0006738
2.877209e+00	1.580335	0.4525454	3.401799	0.0006694	0.0087593	ENSG00000254008.1	LINC00051	FC_P	LINC00051	1.580335	0.0006694
9.293291e+00	1.580194	0.3062413	5.146325	0.0000003	0.0000313	ENSG00000206763.1	RNU6-10P	FC_P	RNU6.10P	1.580194	0.0000003
2.471805e+00	1.576072	0.4460956	3.617895	0.0002970	0.0049046	ENSG00000244157.1	RP11-190P13.1	FC_P	RP11.190P13.1	1.576072	0.0002970
1.223163e+02	-1.575566	0.3809510	-4.247193	0.0000216	0.0007715	ENSG00000227925.1	RP11-191N8.2	FC_P	RP11.191N8.2	-1.575566	0.0000216
3.669417e+00	1.575144	0.4271703	3.663085	0.0002492	0.0043420	ENSG00000227352.1	ARHGEF7-AS1	FC_P	ARHGEF7.AS1	1.575144	0.0002492
6.781356e+01	1.574631	0.2914064	5.363296	0.0000001	0.0000133	ENSG00000250384.1	UBE2CP3	FC_P	UBE2CP3	1.574631	0.0000001
1.885952e+01	1.574345	0.4364137	3.624150	0.0002899	0.0048277	ENSG00000134443.5	GRP	FC_P	GRP	1.574345	0.0002899
1.500103e+01	1.574094	0.3733488	4.096854	0.0000419	0.0012390	ENSG00000248711.1	AC006023.8	FC_P	AC006023.8	1.574094	0.0000419
3.781036e+00	1.572631	0.4267284	3.664927	0.0002474	0.0043269	ENSG00000238189.1	ENOX1-AS2	FC_P	ENOX1.AS2	1.572631	0.0002474
1.396289e+01	1.572490	0.3712866	4.366800	0.0000126	0.0005204	ENSG00000225649.1	AC064875.2	FC_P	AC064875.2	1.572490	0.0000126
1.928630e+03	-1.572385	0.3817415	-4.113961	0.0000389	0.0011880	ENSG00000133661.11	SFTPD	FC_P	SFTPD	-1.572385	0.0000389
2.575936e+03	1.572250	0.3290224	4.772733	0.0000018	0.0001292	ENSG00000204291.6	COL15A1	FC_P	COL15A1	1.572250	0.0000018
4.206173e+01	1.571803	0.4846577	3.321049	0.0008968	0.0107871	ENSG00000271258.1	IGHJ3P	FC_P	IGHJ3P	1.571803	0.0008968
5.855511e+02	1.570895	0.2961939	5.297644	0.0000001	0.0000174	ENSG00000112562.14	SMOC2	FC_P	SMOC2	1.570895	0.0000001
8.531200e+02	1.568845	0.2913241	5.404546	0.0000001	0.0000114	ENSG00000118473.17	SGIP1	FC_P	SGIP1	1.568845	0.0000001
5.099970e+03	-1.568642	0.3010661	-5.209047	0.0000002	0.0000239	ENSG00000136352.13	NKX2-1	FC_P	NKX2.1	-1.568642	0.0000002
6.356051e+00	1.568151	0.4180716	3.723495	0.0001965	0.0036592	ENSG00000239500.2	RP1-169K13.3	FC_P	RP1.169K13.3	1.568151	0.0001965
6.009479e+03	-1.567065	0.3262109	-4.788122	0.0000017	0.0001227	ENSG00000176907.3	C8orf4	FC_P	C8orf4	-1.567065	0.0000017
4.312302e+03	-1.566743	0.3113176	-5.057055	0.0000004	0.0000448	ENSG00000122966.9	CIT	FC_P	CIT	-1.566743	0.0000004
1.878664e+01	1.566675	0.2740288	5.698343	0.0000000	0.0000034	ENSG00000230902.1	FAM204CP	FC_P	FAM204CP	1.566675	0.0000000
3.777355e+00	1.566267	0.4918015	3.940922	0.0000812	0.0019909	ENSG00000199914.1	SNORD114-16	FC_P	SNORD114.16	1.566267	0.0000812
5.624410e+02	1.566081	0.2706046	5.756396	0.0000000	0.0000027	ENSG00000259498.1	RP11-244F12.3	FC_P	RP11.244F12.3	1.566081	0.0000000
4.321970e+01	-1.565805	0.4372370	-3.544631	0.0003932	0.0059252	ENSG00000246740.2	CTD-2382E5.1	FC_P	CTD.2382E5.1	-1.565805	0.0003932
7.670603e+01	-1.563254	0.3563237	-4.381837	0.0000118	0.0004994	ENSG00000235721.1	AC013268.3	FC_P	AC013268.3	-1.563254	0.0000118
1.608364e+03	1.563246	0.3108142	5.010512	0.0000005	0.0000535	ENSG00000148848.10	ADAM12	FC_P	ADAM12	1.563246	0.0000005
6.531793e+00	1.563011	0.3883745	4.005319	0.0000619	0.0016416	ENSG00000261410.1	RP11-543N12.1	FC_P	RP11.543N12.1	1.563011	0.0000619
4.592737e+00	1.562612	0.4753604	3.688669	0.0002254	0.0040364	ENSG00000201689.1	SNORD114-29	FC_P	SNORD114.29	1.562612	0.0002254
3.106513e+01	1.562441	0.4155713	3.824012	0.0001313	0.0027782	ENSG00000271216.1	LINC01050	FC_P	LINC01050	1.562441	0.0001313
1.282062e+03	1.561071	0.3302821	4.763137	0.0000019	0.0001342	ENSG00000174099.6	MSRB3	FC_P	MSRB3	1.561071	0.0000019
1.381420e+01	1.560261	0.3676702	4.258616	0.0000206	0.0007466	ENSG00000258066.1	RP11-781A6.1	FC_P	RP11.781A6.1	1.560261	0.0000206
4.898596e+03	-1.559954	0.3471574	-4.564183	0.0000050	0.0002711	ENSG00000048540.10	LMO3	FC_P	LMO3	-1.559954	0.0000050
1.755089e+03	-1.558633	0.2674637	-5.822818	0.0000000	0.0000021	ENSG00000173599.9	PC	FC_P	PC	-1.558633	0.0000000
1.317731e+01	-1.558186	0.4163704	-3.567899	0.0003599	0.0055683	ENSG00000109991.4	P2RX3	FC_P	P2RX3	-1.558186	0.0003599
3.733031e+02	-1.557663	0.2652533	-5.790451	0.0000000	0.0000023	ENSG00000166816.9	LDHD	FC_P	LDHD	-1.557663	0.0000000
1.641334e+02	1.557163	0.3278493	4.754179	0.0000020	0.0001382	ENSG00000117152.9	RGS4	FC_P	RGS4	1.557163	0.0000020
2.317136e+03	1.556649	0.3996337	3.925508	0.0000865	0.0020842	ENSG00000145423.4	SFRP2	FC_P	SFRP2	1.556649	0.0000865
3.401847e+01	-1.555815	0.4552946	-3.397058	0.0006811	0.0088683	ENSG00000258346.1	RP11-148B3.2	FC_P	RP11.148B3.2	-1.555815	0.0006811
6.280500e+01	1.555751	0.3929189	4.496595	0.0000069	0.0003372	ENSG00000232018.4	AL132709.8	FC_P	AL132709.8	1.555751	0.0000069
5.970118e+01	1.555497	0.2560910	6.113124	0.0000000	0.0000006	ENSG00000271590.1	RP11-181E10.3	FC_P	RP11.181E10.3	1.555497	0.0000000
3.933574e+01	1.554615	0.3596817	4.373596	0.0000122	0.0005100	ENSG00000236841.3	AC007750.5	FC_P	AC007750.5	1.554615	0.0000122
1.164699e+01	1.554434	0.3548469	4.393317	0.0000112	0.0004802	ENSG00000267405.1	CTC-296K1.4	FC_P	CTC.296K1.4	1.554434	0.0000112
1.671627e+01	1.553988	0.4132126	3.856639	0.0001150	0.0025382	ENSG00000232458.1	AC005029.1	FC_P	AC005029.1	1.553988	0.0001150
1.993580e+00	1.553745	0.4626075	3.302968	0.0009567	0.0112793	ENSG00000265552.1	RP11-958F21.3	FC_P	RP11.958F21.3	1.553745	0.0009567
2.895708e+03	-1.553680	0.3254418	-4.723432	0.0000023	0.0001532	ENSG00000100413.12	POLR3H	FC_P	POLR3H	-1.553680	0.0000023
3.180158e+01	-1.553298	0.3917748	-3.975509	0.0000702	0.0017903	ENSG00000223975.1	AP001048.4	FC_P	AP001048.4	-1.553298	0.0000702
1.988534e+01	1.553052	0.3092712	4.973927	0.0000007	0.0000618	ENSG00000204011.4	COL5A1-AS1	FC_P	COL5A1.AS1	1.553052	0.0000007
5.419022e+01	-1.552908	0.4211836	-3.659246	0.0002530	0.0043825	ENSG00000254143.1	RP11-470M17.2	FC_P	RP11.470M17.2	-1.552908	0.0002530
8.710425e+00	1.552312	0.3307160	4.666495	0.0000031	0.0001897	ENSG00000231857.1	MORF4L1P5	FC_P	MORF4L1P5	1.552312	0.0000031
1.251726e+02	-1.550488	0.4039930	-3.864245	0.0001114	0.0024852	ENSG00000269353.1	AC092071.1	FC_P	AC092071.1	-1.550488	0.0001114
7.571153e+00	-1.549230	0.4029496	-3.859760	0.0001135	0.0025180	ENSG00000228559.1	RP3-340B19.3	FC_P	RP3.340B19.3	-1.549230	0.0001135
6.955209e+01	-1.548921	0.3666065	-4.271043	0.0000195	0.0007180	ENSG00000070729.9	CNGB1	FC_P	CNGB1	-1.548921	0.0000195
3.611131e+00	1.546149	0.4719004	3.739977	0.0001840	0.0035064	ENSG00000252009.1	SNORD112	FC_P	SNORD112.1	1.546149	0.0001840
8.844024e+00	1.545781	0.3578716	4.330506	0.0000149	0.0005864	ENSG00000249373.2	RP11-650J17.2	FC_P	RP11.650J17.2	1.545781	0.0000149
1.453988e+01	1.545047	0.3806668	4.128685	0.0000365	0.0011347	ENSG00000254629.1	RP11-160H12.3	FC_P	RP11.160H12.3	1.545047	0.0000365
2.776671e+01	-1.544864	0.4449856	-3.603226	0.0003143	0.0051048	ENSG00000116981.3	NT5C1A	FC_P	NT5C1A	-1.544864	0.0003143
2.248082e+01	1.543153	0.4765384	3.807728	0.0001402	0.0029087	ENSG00000179674.2	ARL14	FC_P	ARL14	1.543153	0.0001402
8.709485e+02	-1.542648	0.3294505	-4.671701	0.0000030	0.0001869	ENSG00000224189.2	HOXD-AS1	FC_P	HOXD.AS1	-1.542648	0.0000030
3.481573e+02	1.542514	0.2793606	5.496172	0.0000000	0.0000076	ENSG00000120820.8	GLT8D2	FC_P	GLT8D2	1.542514	0.0000000
1.482488e+01	1.541988	0.4519687	3.337716	0.0008447	0.0103223	ENSG00000121871.3	SLITRK3	FC_P	SLITRK3	1.541988	0.0008447
1.702940e+01	-1.541802	0.3948889	-3.788423	0.0001516	0.0030722	ENSG00000265388.1	RN7SL391P	FC_P	RN7SL391P	-1.541802	0.0001516
6.630653e+01	1.540826	0.3692300	4.196135	0.0000272	0.0009123	ENSG00000249992.1	TMEM158	FC_P	TMEM158	1.540826	0.0000272
1.822185e+01	1.540214	0.4034427	3.871249	0.0001083	0.0024380	ENSG00000243440.2	AF165138.7	FC_P	AF165138.7	1.540214	0.0001083
4.663674e+02	-1.539099	0.4210036	-3.691403	0.0002230	0.0040047	ENSG00000187048.8	CYP4A11	FC_P	CYP4A11	-1.539099	0.0002230
7.596676e+00	1.537259	0.3818145	3.988930	0.0000664	0.0017235	ENSG00000212204.1	RNA5SP91	FC_P	RNA5SP91	1.537259	0.0000664
5.918072e+03	-1.536418	0.3557752	-4.334793	0.0000146	0.0005775	ENSG00000171476.17	HOPX	FC_P	HOPX	-1.536418	0.0000146
2.370766e+01	1.536415	0.3376453	4.546055	0.0000055	0.0002863	ENSG00000230694.1	RP11-62F24.1	FC_P	RP11.62F24.1	1.536415	0.0000055
3.125993e+00	1.536246	0.3953654	3.849268	0.0001185	0.0025899	ENSG00000265313.1	RP11-567L7.6	FC_P	RP11.567L7.6	1.536246	0.0001185
1.065460e+02	1.536243	0.2929333	5.319523	0.0000001	0.0000160	ENSG00000250280.2	RP11-305O6.3	FC_P	RP11.305O6.3	1.536243	0.0000001
2.219166e+01	-1.536240	0.4823800	-3.706916	0.0002098	0.0038277	ENSG00000206463.6	C6orf205	FC_P	C6orf205	-1.536240	0.0002098
6.080607e+02	1.535745	0.3782227	4.162804	0.0000314	0.0010138	ENSG00000167244.13	IGF2	FC_P	IGF2	1.535745	0.0000314
1.796254e+01	-1.533318	0.4159923	-3.614374	0.0003011	0.0049479	ENSG00000262492.1	RP11-1099M24.8	FC_P	RP11.1099M24.8	-1.533318	0.0003011
3.781246e+00	1.532903	0.4185174	3.730017	0.0001915	0.0035961	ENSG00000222185.1	SNORD113	FC_P	SNORD113	1.532903	0.0001915
5.151126e+00	1.532782	0.3863039	4.124703	0.0000371	0.0011488	ENSG00000265536.1	AL591042.1	FC_P	AL591042.1	1.532782	0.0000371
2.946858e+01	1.532389	0.3382511	4.463509	0.0000081	0.0003799	ENSG00000227496.1	RP11-145A3.1	FC_P	RP11.145A3.1	1.532389	0.0000081
2.237172e+02	1.532171	0.4668705	3.521874	0.0004285	0.0063062	ENSG00000271648.1	IGHV3-11	FC_P	IGHV3.11	1.532171	0.0004285
9.151994e+00	1.531802	0.3984631	3.863041	0.0001120	0.0024915	ENSG00000242941.1	CTD-2325P2.2	FC_P	CTD.2325P2.2	1.531802	0.0001120
1.518135e+01	1.531487	0.2734720	5.571350	0.0000000	0.0000057	ENSG00000248873.1	SERBP1P6	FC_P	SERBP1P6	1.531487	0.0000000
8.307226e+01	1.530250	0.2686073	5.677951	0.0000000	0.0000036	ENSG00000224897.2	RP11-3B12.1	FC_P	RP11.3B12.1	1.530250	0.0000000
9.305709e+00	-1.530117	0.4176587	-3.714309	0.0002038	0.0037465	ENSG00000229272.1	RP11-498J9.2	FC_P	RP11.498J9.2	-1.530117	0.0002038
4.578906e+00	-1.529233	0.5030228	-3.549119	0.0003865	0.0058580	ENSG00000223590.4	C6orf205	FC_P	C6orf205.1	-1.529233	0.0003865
4.863668e+02	1.528042	0.4353673	3.607298	0.0003094	0.0050404	ENSG00000106278.7	PTPRZ1	FC_P	PTPRZ1	1.528042	0.0003094
2.428953e+01	1.527528	0.2938155	5.244359	0.0000002	0.0000208	ENSG00000215933.1	BX119917.1	FC_P	BX119917.1	1.527528	0.0000002
7.507025e+01	-1.527422	0.4386317	-3.647499	0.0002648	0.0045403	ENSG00000214128.6	TMEM213	FC_P	TMEM213	-1.527422	0.0002648
1.147214e+01	-1.526457	0.4238121	-3.576628	0.0003481	0.0054304	ENSG00000253315.1	CTB-11I22.2	FC_P	CTB.11I22.2	-1.526457	0.0003481
3.198663e+00	1.525971	0.4132529	3.546863	0.0003898	0.0058954	ENSG00000258402.1	RP11-516J2.1	FC_P	RP11.516J2.1	1.525971	0.0003898
7.318668e+02	-1.525772	0.2942302	-5.218648	0.0000002	0.0000231	ENSG00000225151.6	AC103965.1	FC_P	AC103965.1	-1.525772	0.0000002
3.819484e+00	-1.525534	0.4493442	-3.384116	0.0007141	0.0091467	ENSG00000267478.1	RP11-815J4.5	FC_P	RP11.815J4.5	-1.525534	0.0007141
8.138247e+01	1.525373	0.2866679	5.255591	0.0000001	0.0000200	ENSG00000073146.11	MOV10L1	FC_P	MOV10L1	1.525373	0.0000001
5.685427e+03	-1.524476	0.3849917	-3.942855	0.0000805	0.0019797	ENSG00000127249.10	ATP13A4	FC_P	ATP13A4	-1.524476	0.0000805
8.506167e+02	1.524248	0.3676329	4.087908	0.0000435	0.0012708	ENSG00000183098.6	GPC6	FC_P	GPC6	1.524248	0.0000435
4.276628e+02	-1.524056	0.3051867	-4.942937	0.0000008	0.0000682	ENSG00000163884.3	KLF15	FC_P	KLF15	-1.524056	0.0000008
2.892711e+01	-1.521232	0.4859591	-3.388861	0.0007018	0.0090438	ENSG00000256691.1	RP11-476M19.3	FC_P	RP11.476M19.3	-1.521232	0.0007018
3.258008e+01	-1.521134	0.3889540	-3.875199	0.0001065	0.0024083	ENSG00000179270.6	C2orf71	FC_P	C2orf71	-1.521134	0.0001065
3.414056e+03	-1.520656	0.2783507	-5.467359	0.0000000	0.0000084	ENSG00000169242.7	EFNA1	FC_P	EFNA1	-1.520656	0.0000000
1.292474e+01	1.518709	0.3577691	4.525576	0.0000060	0.0003065	ENSG00000255649.1	RP11-502N13.2	FC_P	RP11.502N13.2	1.518709	0.0000060
8.019955e+00	-1.518453	0.4410057	-3.358804	0.0007828	0.0097658	ENSG00000250934.1	RP11-71E19.1	FC_P	RP11.71E19.1	-1.518453	0.0007828
1.352664e+03	1.517918	0.2706751	5.590557	0.0000000	0.0000052	ENSG00000139926.11	FRMD6	FC_P	FRMD6	1.517918	0.0000000
3.593490e+02	-1.516537	0.3868729	-3.945193	0.0000797	0.0019688	ENSG00000238042.1	RP11-815M8.1	FC_P	RP11.815M8.1	-1.516537	0.0000797
7.040067e+00	1.516390	0.4131853	3.640622	0.0002720	0.0046254	ENSG00000219404.2	RP11-524C21.1	FC_P	RP11.524C21.1	1.516390	0.0002720
9.964676e+01	1.515492	0.3552552	4.763269	0.0000019	0.0001342	ENSG00000224116.2	INHBA-AS1	FC_P	INHBA.AS1	1.515492	0.0000019
3.549739e+00	-1.514714	0.3953636	-3.796471	0.0001468	0.0030059	ENSG00000219023.1	RP3-340B19.2	FC_P	RP3.340B19.2	-1.514714	0.0001468
2.376663e+00	1.513900	0.4894014	3.316184	0.0009126	0.0109103	ENSG00000222740.1	RNA5SP328	FC_P	RNA5SP328	1.513900	0.0009126
2.539551e+02	1.513642	0.4429984	3.899523	0.0000964	0.0022426	ENSG00000211670.2	IGLV3-9	FC_P	IGLV3.9	1.513642	0.0000964
2.039998e+01	1.513415	0.4380590	3.599265	0.0003191	0.0051491	ENSG00000136267.9	DGKB	FC_P	DGKB	1.513415	0.0003191
5.103272e+00	1.512808	0.4483457	3.661905	0.0002503	0.0043552	ENSG00000250929.2	KB-1639H6.4	FC_P	KB.1639H6.4	1.512808	0.0002503
4.382041e+01	1.512618	0.3158963	4.775410	0.0000018	0.0001282	ENSG00000183055.5	FAM133CP	FC_P	FAM133CP	1.512618	0.0000018
4.407709e+02	1.512338	0.3168504	4.804925	0.0000015	0.0001157	ENSG00000140945.11	CDH13	FC_P	CDH13	1.512338	0.0000015
2.014718e+02	1.511562	0.3060275	4.905404	0.0000009	0.0000795	ENSG00000175600.11	C7orf10	FC_P	C7orf10	1.511562	0.0000009
1.715916e+02	1.511447	0.2460049	6.173251	0.0000000	0.0000005	ENSG00000117586.6	TNFSF4	FC_P	TNFSF4	1.511447	0.0000000
1.440424e+03	-1.510707	0.2442378	-6.164374	0.0000000	0.0000005	ENSG00000099849.10	RASSF7	FC_P	RASSF7	-1.510707	0.0000000
3.369533e+01	1.510408	0.5034489	3.555764	0.0003769	0.0057583	ENSG00000258548.1	LINC00645	FC_P	LINC00645	1.510408	0.0003769
6.399490e+00	1.510336	0.3812797	3.887075	0.0001015	0.0023276	ENSG00000227744.4	AC114788.2	FC_P	AC114788.2	1.510336	0.0001015
5.531161e+00	-1.510055	0.5011370	-3.488099	0.0004865	0.0069339	ENSG00000224396.1	METTL15P3	FC_P	METTL15P3	-1.510055	0.0004865
4.382658e+00	1.508074	0.3874910	3.816779	0.0001352	0.0028385	ENSG00000235389.2	RP11-134K1.3	FC_P	RP11.134K1.3	1.508074	0.0001352
4.816321e+00	1.507351	0.4377859	3.829306	0.0001285	0.0027333	ENSG00000200608.1	SNORD114-11	FC_P	SNORD114.11	1.507351	0.0001285
6.437949e+00	1.507195	0.4139399	3.780913	0.0001563	0.0031202	ENSG00000241042.1	RP11-145M4.1	FC_P	RP11.145M4.1	1.507195	0.0001563
3.858542e+00	1.505461	0.4055178	3.864485	0.0001113	0.0024842	ENSG00000272508.1	RP11-96C23.14	FC_P	RP11.96C23.14	1.505461	0.0001113
4.770128e+02	-1.505458	0.3255398	-4.631408	0.0000036	0.0002157	ENSG00000104369.4	JPH1	FC_P	JPH1	-1.505458	0.0000036
1.996940e+01	1.505106	0.3783876	4.081274	0.0000448	0.0013015	ENSG00000201852.1	RNU6-702P	FC_P	RNU6.702P	1.505106	0.0000448
3.568742e+02	1.504502	0.2809617	5.373085	0.0000001	0.0000131	ENSG00000049192.10	ADAMTS6	FC_P	ADAMTS6	1.504502	0.0000001
6.865166e+01	1.504236	0.3255373	4.815019	0.0000015	0.0001114	ENSG00000224467.1	AC009313.1	FC_P	AC009313.1	1.504236	0.0000015
2.212300e+01	1.504010	0.3493398	4.295074	0.0000175	0.0006632	ENSG00000110675.8	ELMOD1	FC_P	ELMOD1	1.504010	0.0000175
9.321401e+01	1.503987	0.2636059	5.738732	0.0000000	0.0000029	ENSG00000213659.4	RSU1P3	FC_P	RSU1P3	1.503987	0.0000000
1.585019e+03	1.503651	0.3121184	4.847186	0.0000013	0.0000993	ENSG00000172403.6	SYNPO2	FC_P	SYNPO2	1.503651	0.0000013
1.112958e+02	-1.503360	0.3269134	-4.685700	0.0000028	0.0001760	ENSG00000232349.2	YBX1P7	FC_P	YBX1P7	-1.503360	0.0000028
8.532973e+02	-1.503140	0.3820100	-3.962902	0.0000740	0.0018698	ENSG00000124143.6	ARHGAP40	FC_P	ARHGAP40	-1.503140	0.0000740
1.136054e+01	1.502906	0.3695608	4.267082	0.0000198	0.0007272	ENSG00000265470.1	MIR548AQ	FC_P	MIR548AQ	1.502906	0.0000198
4.402676e+02	-1.502363	0.2145530	-6.996187	0.0000000	0.0000000	ENSG00000157992.8	KRTCAP3	FC_P	KRTCAP3	-1.502363	0.0000000
1.605486e+01	1.502272	0.3400933	4.422173	0.0000098	0.0004343	ENSG00000197106.6	SLC6A17	FC_P	SLC6A17	1.502272	0.0000098
2.538391e+00	1.502024	0.4557741	3.321601	0.0008950	0.0107761	ENSG00000272218.1	RP11-11N5.3	FC_P	RP11.11N5.3	1.502024	0.0008950
1.673546e+01	-1.502014	0.4187027	-3.973078	0.0000709	0.0018038	ENSG00000270168.1	LA16c-380H5.4	FC_P	LA16c.380H5.4	-1.502014	0.0000709
9.139078e+02	-1.501855	0.3026810	-4.970060	0.0000007	0.0000623	ENSG00000105707.9	HPN	FC_P	HPN	-1.501855	0.0000007
1.140748e+03	-1.500507	0.2023362	-7.408501	0.0000000	0.0000000	ENSG00000226137.3	BAIAP2-AS1	FC_P	BAIAP2.AS1	-1.500507	0.0000000
1.048512e+02	-1.500299	0.4131333	-3.595005	0.0003244	0.0051946	ENSG00000132874.9	SLC14A2	FC_P	SLC14A2	-1.500299	0.0003244

Pathway enrichment analysis fGSEA

Low TRPA1 is the reference. When TRPA1 is high, pathways shown below are up- or down- regulated

fgsea_res <- fgsea_analysis(DE_res)

## `summarise()` ungrouping output (override with `.groups` argument)

## Warning in fgsea(pathways = gmtPathways(pthw_path), stats = ranks, nperm = 1000): There are ties in the preranked stats (0.03% of the list).
## The order of those tied genes will be arbitrary, which may produce unexpected results.

## Warning in fgsea(pathways = gmtPathways(pthw_path), stats = ranks, nperm = 1000): There are ties in the preranked stats (0.03% of the list).
## The order of those tied genes will be arbitrary, which may produce unexpected results.

## Warning in fgsea(pathways = gmtPathways(pthw_path), stats = ranks, nperm = 1000): There are ties in the preranked stats (0.03% of the list).
## The order of those tied genes will be arbitrary, which may produce unexpected results.

## Warning in fgsea(pathways = gmtPathways(pthw_path), stats = ranks, nperm = 1000): There are ties in the preranked stats (0.03% of the list).
## The order of those tied genes will be arbitrary, which may produce unexpected results.

## Warning in fgsea(pathways = gmtPathways(pthw_path), stats = ranks, nperm = 1000): There are ties in the preranked stats (0.03% of the list).
## The order of those tied genes will be arbitrary, which may produce unexpected results.

## Warning in fgsea(pathways = gmtPathways(pthw_path), stats = ranks, nperm = 1000): There are ties in the preranked stats (0.03% of the list).
## The order of those tied genes will be arbitrary, which may produce unexpected results.

## Warning in fgsea(pathways = gmtPathways(pthw_path), stats = ranks, nperm = 1000): There are ties in the preranked stats (0.03% of the list).
## The order of those tied genes will be arbitrary, which may produce unexpected results.

## Warning in fgsea(pathways = gmtPathways(pthw_path), stats = ranks, nperm = 1000): There are ties in the preranked stats (0.03% of the list).
## The order of those tied genes will be arbitrary, which may produce unexpected results.

## Warning in fgsea(pathways = gmtPathways(pthw_path), stats = ranks, nperm = 1000): There are ties in the preranked stats (0.03% of the list).
## The order of those tied genes will be arbitrary, which may produce unexpected results.

fgp <- fgsea_plot(fgsea_res$res_hm, pathways_title='Hallmark', condition_name='TRPA1 low vs high')

kable(fgp)

pathway	pval	padj	ES	NES	nMoreExtreme	size	state
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	0.0015385	0.0068418	0.6739362	3.161798	0	189	up
HALLMARK_FATTY_ACID_METABOLISM	0.0028090	0.0068418	-0.5953249	-2.865399	0	147	down
HALLMARK_OXIDATIVE_PHOSPHORYLATION	0.0028249	0.0068418	-0.5301295	-2.618666	0	175	down
HALLMARK_ADIPOGENESIS	0.0028736	0.0068418	-0.5116233	-2.528606	0	183	down
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	0.0023981	0.0068418	-0.6120796	-2.404855	0	46	down
HALLMARK_MYC_TARGETS_V2	0.0024876	0.0068418	-0.5624492	-2.292563	0	57	down
HALLMARK_ESTROGEN_RESPONSE_EARLY	0.0027778	0.0068418	-0.4464027	-2.229052	0	191	down
HALLMARK_P53_PATHWAY	0.0028329	0.0068418	-0.4335855	-2.164594	0	190	down
HALLMARK_HEME_METABOLISM	0.0027624	0.0068418	-0.4268950	-2.118259	0	179	down
HALLMARK_ESTROGEN_RESPONSE_LATE	0.0027322	0.0068418	-0.4195856	-2.104910	0	193	down
HALLMARK_ALLOGRAFT_REJECTION	0.0015175	0.0068418	0.4474463	2.100379	0	187	up
HALLMARK_GLYCOLYSIS	0.0028736	0.0068418	-0.4126562	-2.047099	0	188	down
HALLMARK_PEROXISOME	0.0025000	0.0068418	-0.4318012	-1.977031	0	103	down
HALLMARK_XENOBIOTIC_METABOLISM	0.0028736	0.0068418	-0.3897914	-1.933672	0	188	down
HALLMARK_CHOLESTEROL_HOMEOSTASIS	0.0024691	0.0068418	-0.4461706	-1.882386	0	69	down
HALLMARK_DNA_REPAIR	0.0027473	0.0068418	-0.3818767	-1.832369	0	141	down
HALLMARK_ANGIOGENESIS	0.0016807	0.0068418	0.5106221	1.778316	0	35	up
HALLMARK_BILE_ACID_METABOLISM	0.0025707	0.0068418	-0.3688872	-1.702384	0	109	down
HALLMARK_KRAS_SIGNALING_UP	0.0015408	0.0068418	0.3427265	1.608198	0	190	up
HALLMARK_INFLAMMATORY_RESPONSE	0.0015723	0.0068418	0.3352331	1.574628	0	193	up
HALLMARK_MYC_TARGETS_V1	0.0028409	0.0068418	-0.3110126	-1.549825	0	189	down
HALLMARK_UV_RESPONSE_DN	0.0031397	0.0071357	0.3318998	1.486112	1	136	up
HALLMARK_UV_RESPONSE_UP	0.0056180	0.0122130	-0.3150255	-1.516271	1	147	down
HALLMARK_G2M_CHECKPOINT	0.0060698	0.0125786	0.3037292	1.425749	3	187	up
HALLMARK_COMPLEMENT	0.0062893	0.0125786	0.2984481	1.401845	3	193	up
HALLMARK_HYPOXIA	0.0084270	0.0162057	-0.2809825	-1.391582	2	180	down
HALLMARK_APOPTOSIS	0.0218579	0.0404776	-0.2697592	-1.313157	7	155	down
HALLMARK_TNFA_SIGNALING_VIA_NFKB	0.0249221	0.0445038	0.2785968	1.310677	15	195	up
HALLMARK_MYOGENESIS	0.0261941	0.0451623	0.2846638	1.335747	16	190	up

fgp <- fgsea_plot(fgsea_res$res_c1, pathways_title='C1 positional genes', condition_name='TRPA1 low vs high')

kable(fgp)

pathway	pval	padj	ES	NES	nMoreExtreme	size	state
chr17q25	0.0028090	0.0131392	-0.5540986	-2.803496	0	202	down
chr1q22	0.0024096	0.0131392	-0.6980236	-2.742202	0	53	down
chr9q34	0.0028169	0.0131392	-0.5374793	-2.733427	0	210	down
chr12q21	0.0016502	0.0131392	0.6242482	2.486050	0	66	up
chr16p11	0.0026882	0.0131392	-0.5251991	-2.410241	0	120	down
chr12p11	0.0017699	0.0131392	0.6633026	2.394753	0	41	up
chr12q15	0.0018051	0.0131392	0.6739325	2.343853	0	34	up
chr12q14	0.0017094	0.0131392	0.5899682	2.272550	0	55	up
chr1q21	0.0027778	0.0131392	-0.4519925	-2.265587	0	191	down
chr3p21	0.0028409	0.0131392	-0.4385913	-2.229828	0	211	down
chr7p15	0.0016807	0.0131392	0.5676641	2.218463	0	61	up
chr3q23	0.0017921	0.0131392	0.6326371	2.218442	0	35	up
chr1p22	0.0016420	0.0131392	0.5385445	2.214290	0	81	up
chr1p31	0.0015873	0.0131392	0.5013006	2.208660	0	120	up
chr16q22	0.0027322	0.0131392	-0.4713100	-2.192541	0	132	down
chr1p34	0.0027624	0.0131392	-0.4347676	-2.183732	0	192	down
chr11q14	0.0016584	0.0131392	0.5231500	2.132327	0	76	up
chr7p14	0.0015723	0.0131392	0.4855863	2.120959	0	107	up
chr2q22	0.0018727	0.0131392	0.7524950	2.110396	0	14	up
chr3p24	0.0017007	0.0131392	0.5401576	2.071583	0	54	up
chr13q14	0.0016051	0.0131392	0.4508598	2.064126	0	151	up
chr15q21	0.0015723	0.0131392	0.4752167	2.058117	0	102	up
chr5p13	0.0016639	0.0131392	0.4944827	2.049808	0	84	up
chr3q13	0.0015798	0.0131392	0.4619823	2.042202	0	121	up
chr2q32	0.0016750	0.0131392	0.5168686	2.031683	0	63	up
chr1p33	0.0022173	0.0131392	-0.5351399	-2.008367	0	40	down
chr16q21	0.0022883	0.0131392	-0.5282785	-1.990416	0	41	down
chr6q23	0.0016807	0.0131392	0.5005102	1.956021	0	61	up
chr7q21	0.0016260	0.0131392	0.4621638	1.955557	0	95	up
chr1p35	0.0026525	0.0131392	-0.4391349	-1.952368	0	99	down

fgp <- fgsea_plot(fgsea_res$res_c2, pathways_title='C2 curated genes', condition_name='TRPA1 low vs high')

kable(fgp)

pathway	pval	padj	ES	NES	nMoreExtreme	size	state
SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4	0.0027701	0.0232728	-0.7620073	-3.792788	0	184	down
CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_UP	0.0031348	0.0232728	-0.6560515	-3.586314	0	406	down
ANASTASSIOU_MULTICANCER_INVASIVENESS_SIGNATURE	0.0016779	0.0232728	0.8581136	3.393820	0	62	up
LIM_MAMMARY_STEM_CELL_DN	0.0031646	0.0232728	-0.6174004	-3.361235	0	387	down
SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP	0.0014514	0.0232728	0.6542663	3.305901	0	331	up
WAMUNYOKOLI_OVARIAN_CANCER_LMP_UP	0.0028409	0.0232728	-0.6297646	-3.277198	0	256	down
VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP	0.0015528	0.0232728	0.6983670	3.233029	0	161	up
HOLLERN_EMT_BREAST_TUMOR_DN	0.0025773	0.0232728	-0.6827411	-3.196734	0	114	down
NIKOLSKY_BREAST_CANCER_16P13_AMPLICON	0.0025063	0.0232728	-0.6934069	-3.186439	0	105	down
REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION	0.0024876	0.0232728	-0.7141323	-3.176153	0	86	down
TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_DUCTAL_NORMAL_UP	0.0016779	0.0232728	0.7789150	3.098541	0	66	up
CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_UP	0.0025773	0.0232728	-0.6599321	-3.093311	0	113	down
KEGG_RIBOSOME	0.0024938	0.0232728	-0.7039892	-3.086477	0	81	down
COLDREN_GEFITINIB_RESISTANCE_DN	0.0028986	0.0232728	-0.6010449	-3.046498	0	206	down
REACTOME_SELENOAMINO_ACID_METABOLISM	0.0025189	0.0232728	-0.6570245	-3.011520	0	102	down
REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE	0.0025381	0.0232728	-0.6521263	-2.988792	0	104	down
REACTOME_NONSENSE_MEDIATED_DECAY_NMD	0.0025510	0.0232728	-0.6467621	-2.982963	0	108	down
REACTOME_TRANSLATION	0.0029155	0.0232728	-0.5647839	-2.943763	0	262	down
REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY	0.0025445	0.0232728	-0.6453424	-2.921069	0	94	down
NIKOLSKY_BREAST_CANCER_1Q21_AMPLICON	0.0022075	0.0232728	-0.8162160	-2.898852	0	33	down
REACTOME_EUKARYOTIC_TRANSLATION_INITIATION	0.0026385	0.0232728	-0.6213136	-2.888042	0	112	down
BOQUEST_STEM_CELL_UP	0.0015528	0.0232728	0.5911478	2.874875	0	248	up
MOOTHA_MITOCHONDRIA	0.0031348	0.0232728	-0.5236436	-2.863479	0	404	down
MOOTHA_HUMAN_MITODB_6_2002	0.0031447	0.0232728	-0.5212564	-2.841061	0	395	down
GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN	0.0032051	0.0232728	-0.5324299	-2.810825	0	308	down
CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN	0.0014368	0.0232728	0.5419776	2.807116	0	433	up
VANTVEER_BREAST_CANCER_ESR1_UP	0.0028571	0.0232728	-0.5562090	-2.802118	0	194	down
LU_EZH2_TARGETS_UP	0.0028329	0.0232728	-0.5371526	-2.799113	0	257	down
REACTOME_RRNA_PROCESSING	0.0027701	0.0232728	-0.5562635	-2.768726	0	184	down
LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_DN	0.0024938	0.0232728	-0.5990959	-2.750040	0	103	down

fgp <- fgsea_plot(fgsea_res$res_c3, pathways_title='C3 regulatory target genes', condition_name='TRPA1 low vs high')

kable(fgp)

pathway	pval	padj	ES	NES	nMoreExtreme	size	state
MCM2_TARGET_GENES	0.0024096	0.0172521	-0.6004621	-2.607100	0	76	down
KLF14_TARGET_GENES	0.0028902	0.0172521	-0.5015076	-2.534658	0	215	down
YBX3_TARGET_GENES	0.0026738	0.0172521	-0.4767254	-2.342535	0	163	down
MIR3129_3P	0.0016340	0.0172521	0.5401223	2.327087	0	97	up
HES4_TARGET_GENES	0.0034483	0.0172521	-0.4163147	-2.304145	0	508	down
NR1H4_TARGET_GENES	0.0032362	0.0172521	-0.4294581	-2.292309	0	350	down
MIR5583_5P	0.0016340	0.0172521	0.5232627	2.254448	0	97	up
CDC73_TARGET_GENES	0.0035211	0.0172521	-0.4051076	-2.243563	0	538	down
SNRNP70_TARGET_GENES	0.0027100	0.0172521	-0.4604837	-2.239590	0	153	down
DLX6_TARGET_GENES	0.0033898	0.0172521	-0.4066286	-2.237575	0	486	down
GGAANCGGAANY_UNKNOWN	0.0026385	0.0172521	-0.4910859	-2.231570	0	103	down
ADNP_TARGET_GENES	0.0035336	0.0172521	-0.3962869	-2.200792	0	543	down
SP1_Q6_01	0.0029499	0.0172521	-0.4279328	-2.182687	0	234	down
ZNF354B_TARGET_GENES	0.0026810	0.0172521	-0.4411021	-2.166373	0	165	down
HOXD11_TARGET_GENES	0.0026738	0.0172521	-0.4611489	-2.162526	0	121	down
HJURP_TARGET_GENES	0.0023256	0.0172521	-0.5408384	-2.158140	0	51	down
ATOH1_TARGET_GENES	0.0027855	0.0172521	-0.4301927	-2.155108	0	194	down
MIR3646	0.0013369	0.0172521	0.3995005	2.151771	0	797	up
PCGF1_TARGET_GENES	0.0033333	0.0172521	-0.3920384	-2.150324	0	466	down
MIR92A_2_5P	0.0027624	0.0172521	-0.4282733	-2.146664	0	187	down
ZMYM2_TARGET_GENES	0.0026316	0.0172521	-0.4623409	-2.145527	0	115	down
MIR423_5P	0.0026110	0.0172521	-0.4526046	-2.143738	0	129	down
MIR607	0.0013055	0.0172521	0.3948528	2.142111	0	906	up
TOP2B_TARGET_GENES	0.0033784	0.0172521	-0.3859978	-2.135174	0	502	down
MIR5009_5P	0.0017391	0.0172521	0.5487183	2.129045	0	55	up
ETS2_TARGET_GENES	0.0032258	0.0172521	-0.3994484	-2.128711	0	348	down
MIR3662	0.0013210	0.0172521	0.3901927	2.112240	0	897	up
MIR8058	0.0017513	0.0172521	0.5822842	2.102765	0	40	up
MIR6836_5P	0.0026385	0.0172521	-0.4539634	-2.102459	0	114	down
MIR4283	0.0027855	0.0172521	-0.4192818	-2.100449	0	194	down

fgp <- fgsea_plot(fgsea_res$res_c4, pathways_title='C4 cancer', condition_name='TRPA1 low vs high')

kable(fgp)

pathway	pval	padj	ES	NES	nMoreExtreme	size	state
MODULE_47	0.0015267	0.0124089	0.6533425	3.131514	0	214	up
MORF_NME2	0.0025253	0.0124089	-0.6383365	-3.058289	0	141	down
GCM_TPT1	0.0023041	0.0124089	-0.7197048	-2.952418	0	59	down
MODULE_93	0.0026385	0.0124089	-0.5887097	-2.878722	0	176	down
MODULE_180	0.0023641	0.0124089	-0.6123511	-2.840095	0	115	down
MORF_ACTG1	0.0023474	0.0124089	-0.5894037	-2.797677	0	127	down
MORF_TPT1	0.0023529	0.0124089	-0.6308074	-2.780150	0	92	down
GNF2_PTX3	0.0018051	0.0124089	0.7822413	2.762134	0	35	up
GNF2_EIF3S6	0.0023753	0.0124089	-0.5963867	-2.739096	0	110	down
GNF2_TPT1	0.0022676	0.0124089	-0.7382220	-2.738484	0	36	down
GNF2_GLTSCR2	0.0022371	0.0124089	-0.7762522	-2.734879	0	29	down
MODULE_139	0.0022779	0.0124089	-0.6299461	-2.716218	0	76	down
MORF_NPM1	0.0025189	0.0124089	-0.5533189	-2.676354	0	149	down
GNF2_CDH11	0.0018083	0.0124089	0.8106653	2.654171	0	25	up
GNF2_MMP1	0.0017699	0.0124089	0.7540945	2.619930	0	31	up
MODULE_221	0.0022371	0.0124089	-0.7367136	-2.595577	0	29	down
MORF_PHB	0.0023585	0.0124089	-0.5610894	-2.586936	0	113	down
MORF_PPP1CA	0.0025445	0.0124089	-0.5342483	-2.585427	0	153	down
MODULE_184	0.0022222	0.0124089	-0.7340145	-2.585372	0	28	down
MORF_AP2M1	0.0027624	0.0124089	-0.5189705	-2.577038	0	203	down
GNF2_ST13	0.0022989	0.0124089	-0.6295837	-2.573092	0	58	down
MODULE_152	0.0023753	0.0124089	-0.5641266	-2.571329	0	106	down
MORF_IKBKG	0.0023585	0.0124089	-0.5433116	-2.567762	0	126	down
MORF_GPX4	0.0022472	0.0124089	-0.6426144	-2.546974	0	50	down
MODULE_83	0.0028986	0.0124089	-0.4867621	-2.543899	0	290	down
MODULE_151	0.0028902	0.0124089	-0.4861352	-2.543296	0	289	down
MODULE_29	0.0021882	0.0124089	-0.7313627	-2.531511	0	26	down
MORF_CSNK2B	0.0027473	0.0124089	-0.4848982	-2.503487	0	258	down
MODULE_43	0.0023364	0.0124089	-0.5599176	-2.500084	0	95	down
GNF2_HPN	0.0024390	0.0124089	-0.5312804	-2.482505	0	124	down

fgp <- fgsea_plot(fgsea_res$res_c5, pathways_title='C5 GO genes', condition_name='TRPA1 low vs high')

kable(fgp)

pathway	pval	padj	ES	NES	nMoreExtreme	size	state
GO_CYTOSOLIC_RIBOSOME	0.0024038	0.0399244	-0.6779960	-3.003977	0	95	down
GO_STRUCTURAL_CONSTITUENT_OF_RIBOSOME	0.0024570	0.0399244	-0.6157863	-3.003516	0	152	down
GO_RIBOSOME	0.0027701	0.0399244	-0.5929556	-2.994946	0	211	down
GO_RIBOSOMAL_SUBUNIT	0.0026738	0.0399244	-0.6094129	-2.987261	0	172	down
GO_LARGE_RIBOSOMAL_SUBUNIT	0.0023753	0.0399244	-0.6379143	-2.922854	0	108	down
GO_NUCLEAR_TRANSCRIBED_MRNA_CATABOLIC_PROCESS_NONSENSE_MEDIATED_DECAY	0.0023810	0.0399244	-0.6263286	-2.890226	0	114	down
GO_CYTOSOLIC_LARGE_RIBOSOMAL_SUBUNIT	0.0023256	0.0399244	-0.7209130	-2.843214	0	53	down
GO_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE	0.0023866	0.0399244	-0.6375241	-2.828872	0	94	down
GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_CH_CH_GROUP_OF_DONORS	0.0023202	0.0399244	-0.7035074	-2.800764	0	55	down
GO_COENZYME_BINDING	0.0028329	0.0399244	-0.5385803	-2.796098	0	271	down
GO_MONOCARBOXYLIC_ACID_CATABOLIC_PROCESS	0.0024272	0.0399244	-0.5998700	-2.794386	0	121	down
GO_COLLAGEN_BINDING	0.0017391	0.0399244	0.6833435	2.734113	0	64	up
GO_ORGANIC_ACID_CATABOLIC_PROCESS	0.0027473	0.0399244	-0.5288423	-2.729203	0	251	down
GO_FATTY_ACID_CATABOLIC_PROCESS	0.0024272	0.0399244	-0.6106636	-2.724092	0	98	down
GO_FATTY_ACID_BETA_OXIDATION	0.0023810	0.0399244	-0.6569746	-2.716592	0	67	down
GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_ENDOPLASMIC_RETICULUM	0.0024155	0.0399244	-0.5893202	-2.683349	0	106	down
GO_PROTEIN_TARGETING_TO_MEMBRANE	0.0026596	0.0399244	-0.5462283	-2.679568	0	173	down
GO_RIBOSOMAL_LARGE_SUBUNIT_BIOGENESIS	0.0022883	0.0399244	-0.6462127	-2.645053	0	62	down
GO_COFACTOR_BIOSYNTHETIC_PROCESS	0.0027701	0.0399244	-0.5161291	-2.605578	0	209	down
GO_FATTY_ACID_METABOLIC_PROCESS	0.0029240	0.0399244	-0.4839875	-2.592955	0	342	down
GO_VIRAL_GENE_EXPRESSION	0.0026316	0.0399244	-0.5207435	-2.589722	0	185	down
GO_RIBOSOME_BIOGENESIS	0.0027778	0.0399244	-0.4991618	-2.587103	0	259	down
GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_CH_OH_GROUP_OF_DONORS	0.0023753	0.0399244	-0.5573973	-2.582865	0	116	down
GO_COLLAGEN_FIBRIL_ORGANIZATION	0.0017361	0.0399244	0.6681461	2.572845	0	51	up
GO_CELLULAR_AMINO_ACID_CATABOLIC_PROCESS	0.0024096	0.0399244	-0.5553400	-2.571487	0	117	down
GO_COENZYME_METABOLIC_PROCESS	0.0026738	0.0399244	-0.4926671	-2.539616	0	232	down
GO_PROTEIN_LOCALIZATION_TO_ENDOPLASMIC_RETICULUM	0.0025063	0.0399244	-0.5401434	-2.538199	0	128	down
GO_MITOCHONDRIAL_GENE_EXPRESSION	0.0024938	0.0399244	-0.5193559	-2.521252	0	149	down
GO_MITOCHONDRIAL_TRANSLATION	0.0024691	0.0399244	-0.5353643	-2.514587	0	127	down
GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_MEMBRANE	0.0028169	0.0399244	-0.4773437	-2.513247	0	296	down

fgp <- fgsea_plot(fgsea_res$res_c6, pathways_title='C6 oncogenic', condition_name='TRPA1 low vs high')

kable(fgp)

pathway	pval	padj	ES	NES	nMoreExtreme	size	state
CAMP_UP.V1_UP	0.0027778	0.0132283	-0.4694873	-2.329857	0	181	down
MYC_UP.V1_UP	0.0027473	0.0132283	-0.4713650	-2.296250	0	157	down
SINGH_KRAS_DEPENDENCY_SIGNATURE	0.0021186	0.0132283	-0.7057766	-2.198727	0	19	down
LEF1_UP.V1_DN	0.0027933	0.0132283	-0.4363336	-2.151677	0	173	down
SIRNA_EIF4GI_UP	0.0024272	0.0132283	-0.4671653	-2.066444	0	87	down
AKT_UP_MTOR_DN.V1_UP	0.0027933	0.0132283	-0.4115567	-2.021627	0	166	down
ERBB2_UP.V1_UP	0.0027778	0.0132283	-0.4062796	-2.006640	0	175	down
EIF4E_UP	0.0024510	0.0132283	-0.4526974	-1.998095	0	88	down
MEK_UP.V1_UP	0.0027778	0.0132283	-0.4040885	-1.995818	0	175	down
VEGF_A_UP.V1_DN	0.0015649	0.0132283	0.4280704	1.993965	0	184	up
SIRNA_EIF4GI_DN	0.0016835	0.0132283	0.4763496	1.981967	0	88	up
BMI1_DN_MEL18_DN.V1_UP	0.0015649	0.0132283	0.4340218	1.937288	0	135	up
RAPA_EARLY_UP.V1_DN	0.0028011	0.0132283	-0.3893978	-1.911373	0	167	down
RB_P107_DN.V1_DN	0.0026810	0.0132283	-0.4130143	-1.907431	0	113	down
PIGF_UP.V1_UP	0.0015576	0.0132283	0.4078524	1.896010	0	181	up
LEF1_UP.V1_UP	0.0015528	0.0132283	0.4011926	1.859435	0	179	up
STK33_DN	0.0028902	0.0132283	-0.3554830	-1.856429	0	249	down
PDGF_ERK_DN.V1_DN	0.0027473	0.0132283	-0.3842053	-1.839887	0	141	down
AKT_UP.V1_UP	0.0027397	0.0132283	-0.3768202	-1.831308	0	152	down
E2F3_UP.V1_DN	0.0028329	0.0132283	-0.3770684	-1.791267	0	137	down
ESC_J1_UP_EARLY.V1_UP	0.0027100	0.0132283	-0.3600059	-1.749696	0	151	down
PRC2_EED_UP.V1_DN	0.0027933	0.0132283	-0.3517090	-1.744428	0	179	down
STK33_NOMO_DN	0.0029762	0.0132283	-0.3296820	-1.721260	0	254	down
CYCLIN_D1_UP.V1_UP	0.0027933	0.0132283	-0.3464474	-1.708424	0	173	down
RB_DN.V1_UP	0.0026738	0.0132283	-0.3644981	-1.706706	0	123	down
BRCA1_DN.V1_UP	0.0015974	0.0132283	0.3907580	1.696965	0	111	up
SRC_UP.V1_UP	0.0028169	0.0132283	-0.3524269	-1.696265	0	148	down
GCNP_SHH_UP_LATE.V1_DN	0.0028011	0.0132283	-0.3421416	-1.679414	0	167	down
PTEN_DN.V1_UP	0.0015601	0.0132283	0.3704055	1.678552	0	153	up
CYCLIN_D1_KE_.V1_UP	0.0027855	0.0132283	-0.3391235	-1.678220	0	178	down

fgp <- fgsea_plot(fgsea_res$res_c7, pathways_title='C7 immunologic', condition_name='TRPA1 low vs high')

kable(fgp)

pathway	pval	padj	ES	NES	nMoreExtreme	size	state
GSE45837_WT_VS_GFI1_KO_PDC_DN	0.0028571	0.0131487	-0.5874269	-2.897186	0	180	down
GSE9006_TYPE_1_VS_TYPE_2_DIABETES_PBMC_AT_DX_UP	0.0028011	0.0131487	-0.5722605	-2.841540	0	187	down
GSE14000_TRANSLATED_RNA_VS_MRNA_DC_DN	0.0027473	0.0131487	-0.5465548	-2.664065	0	160	down
GSE369_PRE_VS_POST_IL6_INJECTION_SOCS3_KO_LIVER_DN	0.0028011	0.0131487	-0.5327159	-2.645182	0	187	down
GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8A_DC_IFNAR_KO_UP	0.0028329	0.0131487	-0.5399345	-2.641877	0	175	down
GSE42021_CD24LO_TREG_VS_CD24LO_TCONV_THYMUS_DN	0.0028329	0.0131487	-0.5195499	-2.571862	0	185	down
GSE21678_WT_VS_FOXO1_FOXO3_KO_TREG_DN	0.0028736	0.0131487	-0.5263083	-2.566534	0	174	down
GSE16385_MONOCYTE_VS_12H_IL4_TREATED_MACROPHAGE_DN	0.0028329	0.0131487	-0.5182001	-2.554260	0	183	down
GSE45365_WT_VS_IFNAR_KO_CD11B_DC_MCMV_INFECTION_UP	0.0028329	0.0131487	-0.5217021	-2.547915	0	168	down
GSE15735_CTRL_VS_HDAC_INHIBITOR_TREATED_CD4_TCELL_12H_UP	0.0028169	0.0131487	-0.5132211	-2.539276	0	184	down
GSE360_CTRL_VS_L_DONOVANI_MAC_UP	0.0028329	0.0131487	-0.5115894	-2.532456	0	185	down
GSE9006_HEALTHY_VS_TYPE_2_DIABETES_PBMC_AT_DX_UP	0.0028249	0.0131487	-0.5102332	-2.521493	0	181	down
GSE22886_DAY1_VS_DAY7_MONOCYTE_IN_CULTURE_DN	0.0027778	0.0131487	-0.5092085	-2.515549	0	179	down
GSE42724_NAIVE_VS_B1_BCELL_DN	0.0027701	0.0131487	-0.5077368	-2.509721	0	178	down
GSE3920_UNTREATED_VS_IFNG_TREATED_ENDOTHELIAL_CELL_DN	0.0028329	0.0131487	-0.5063666	-2.495932	0	183	down
GSE43863_NAIVE_VS_LY6C_LOW_CXCR5NEG_CD4_EFF_TCELL_D6_LCMV_DN	0.0028249	0.0131487	-0.5049015	-2.472603	0	173	down
GSE36527_CD69_NEG_VS_POS_TREG_CD62L_LOS_KLRG1_NEG_DN	0.0028329	0.0131487	-0.4952493	-2.441133	0	183	down
GSE24210_CTRL_VS_IL35_TREATED_TCONV_CD4_TCELL_DN	0.0028169	0.0131487	-0.4897030	-2.422915	0	184	down
GSE42021_CD24HI_TREG_VS_CD24HI_TCONV_THYMUS_UP	0.0028329	0.0131487	-0.4914981	-2.422643	0	183	down
GSE45365_WT_VS_IFNAR_KO_CD8A_DC_UP	0.0028329	0.0131487	-0.4852031	-2.391615	0	183	down
GSE369_IFNG_KO_VS_WT_LIVER_DN	0.0028571	0.0131487	-0.4819838	-2.377142	0	180	down
GSE39864_WT_VS_GATA3_KO_TREG_DN	0.0028653	0.0131487	-0.4805446	-2.365280	0	182	down
GSE27434_WT_VS_DNMT1_KO_TREG_UP	0.0027701	0.0131487	-0.4779647	-2.362559	0	178	down
GSE42021_TREG_PLN_VS_CD24HI_TREG_THYMUS_DN	0.0028169	0.0131487	-0.4753328	-2.351815	0	184	down
GSE20727_CTRL_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_UP	0.0027778	0.0131487	-0.4752200	-2.347641	0	179	down
GSE22589_HEALTHY_VS_SIV_INFECTED_DC_UP	0.0027778	0.0131487	-0.4740282	-2.341754	0	179	down
GSE17721_CTRL_VS_GARDIQUIMOD_8H_BMDC_UP	0.0028169	0.0131487	-0.4726796	-2.338688	0	184	down
GSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_DN	0.0028011	0.0131487	-0.4702614	-2.335067	0	187	down
GSE2706_UNSTIM_VS_8H_LPS_AND_R848_DC_UP	0.0027778	0.0131487	-0.4713146	-2.328348	0	179	down
GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN	0.0028329	0.0131487	-0.4698153	-2.325667	0	185	down

fgp <- fgsea_plot(fgsea_res$res_msg, pathways_title='All signatures', condition_name='TRPA1 low vs high')

kable(fgp)

pathway	pval	padj	ES	NES	nMoreExtreme	size	state
SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4	0.0028818	0.0201079	-0.7620073	-3.824581	0	184	down
ANASTASSIOU_MULTICANCER_INVASIVENESS_SIGNATURE	0.0016611	0.0201079	0.8581136	3.341093	0	62	up
chr16p13	0.0030581	0.0201079	-0.6303105	-3.334673	0	272	down
WAMUNYOKOLI_OVARIAN_CANCER_LMP_UP	0.0029940	0.0201079	-0.6297646	-3.295148	0	256	down
SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP	0.0015038	0.0201079	0.6542663	3.261850	0	331	up
NIKOLSKY_BREAST_CANCER_16P13_AMPLICON	0.0026525	0.0201079	-0.6934069	-3.202030	0	105	down
VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP	0.0015552	0.0201079	0.6983670	3.195344	0	161	up
REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION	0.0025974	0.0201079	-0.7141323	-3.191795	0	86	down
HOLLERN_EMT_BREAST_TUMOR_DN	0.0027322	0.0201079	-0.6827411	-3.176297	0	114	down
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	0.0015221	0.0201079	0.6739362	3.153720	0	189	up
MODULE_47	0.0015152	0.0201079	0.6533425	3.105321	0	214	up
GO_CYTOSOLIC_RIBOSOME	0.0025840	0.0201079	-0.6779960	-3.094192	0	95	down
KEGG_RIBOSOME	0.0026882	0.0201079	-0.7039892	-3.091734	0	81	down
MORF_NME2	0.0028571	0.0201079	-0.6383365	-3.088148	0	141	down
COLDREN_GEFITINIB_RESISTANCE_DN	0.0029240	0.0201079	-0.6010449	-3.068822	0	206	down
CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_UP	0.0027100	0.0201079	-0.6599321	-3.065326	0	113	down
TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_DUCTAL_NORMAL_UP	0.0016556	0.0201079	0.7789150	3.058841	0	66	up
GO_RIBOSOMAL_SUBUNIT	0.0028409	0.0201079	-0.6094129	-3.044476	0	172	down
GO_RIBOSOME	0.0029070	0.0201079	-0.5929556	-3.037682	0	211	down
REACTOME_SELENOAMINO_ACID_METABOLISM	0.0026525	0.0201079	-0.6570245	-3.013607	0	102	down
GO_STRUCTURAL_CONSTITUENT_OF_RIBOSOME	0.0029499	0.0201079	-0.6157863	-3.005280	0	152	down
REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE	0.0026455	0.0201079	-0.6521263	-3.004705	0	104	down
REACTOME_NONSENSE_MEDIATED_DECAY_NMD	0.0026455	0.0201079	-0.6467621	-2.989497	0	108	down
REACTOME_TRANSLATION	0.0030395	0.0201079	-0.5647839	-2.969292	0	262	down
GCM_TPT1	0.0024752	0.0201079	-0.7197048	-2.954000	0	59	down
GO_LARGE_RIBOSOMAL_SUBUNIT	0.0026455	0.0201079	-0.6379143	-2.948600	0	108	down
MODULE_93	0.0029070	0.0201079	-0.5887097	-2.946597	0	176	down
NIKOLSKY_BREAST_CANCER_1Q21_AMPLICON	0.0022676	0.0201079	-0.8162160	-2.941154	0	33	down
GSE45837_WT_VS_GFI1_KO_PDC_DN	0.0028902	0.0201079	-0.5874269	-2.940907	0	180	down
REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY	0.0025974	0.0201079	-0.6453424	-2.938375	0	94	down